A phase Ia study to assess the safety and immunogenicity of new malaria vaccine candidates ChAd63 CS administered alone and with MVA CS.

by Eoghan de Barra, Susanne H Hodgson, Katie J Ewer, Carly M Bliss, Kerrie Hennigan, Ann Collins, Eleanor Berrie, Alison M Lawrie, Sarah C Gilbert, Alfredo Nicosia, Samuel J McConkey, Adrian V S Hill
Published 2014-01-01

Alternate aerosol and systemic immunisation with a recombinant viral vector for tuberculosis, MVA85A: A phase I randomised controlled trial.

by Zita-Rose Manjaly Thomas, Iman Satti, Julia L Marshall, Stephanie A Harris, Raquel Lopez Ramon, Ali Hamidi, Alice Minhinnick, Michael Riste, Lisa Stockdale, Alison M Lawrie, Samantha Vermaak, Morven Wilkie, Henry Bettinson, Helen McShane
Published 2019-04-01

Safety and Immunogenicity of a Novel Recombinant Simian Adenovirus ChAdOx2 as a Vectored Vaccine

by Pedro M. Folegatti, Duncan Bellamy, Rachel Roberts, Jonathan Powlson, Nick J. Edwards, Catherine F. Mair, Georgina Bowyer, Ian Poulton, Celia H. Mitton, Nicky Green, Eleanor Berrie, Alison M. Lawrie, Adrian V.S. Hill, Katie J. Ewer, John Hermon-Taylor, Sarah C. Gilbert
Published 2019-05-01

Safety and Immunogenicity of Adenovirus and Poxvirus Vectored Vaccines against a Mycobacterium Avium Complex Subspecies

by Pedro M. Folegatti, Amy Flaxman, Daniel Jenkin, Rebecca Makinson, Lucy Kingham-Page, Duncan Bellamy, Fernando Ramos Lopez, Jonathan Sheridan, Ian Poulton, Jeremy Aboagye, Nguyen Tran, Celia Mitton, Rachel Roberts, Alison M. Lawrie, Adrian V. S. Hill, Katie J. Ewer, Sarah Gilbert
Published 2021-03-01

Optimising Controlled Human Malaria Infection Studies Using Cryopreserved P. falciparum Parasites Administered by Needle and Syringe.

by Susanne H Sheehy, Alexandra J Spencer, Alexander D Douglas, B Kim Lee Sim, Rhea J Longley, Nick J Edwards, Ian D Poulton, Domtila Kimani, Andrew R Williams, Nicholas A Anagnostou, Rachel Roberts, Simon Kerridge, Merryn Voysey, Eric R James, Peter F Billingsley, Anusha Gunasekera, Alison M Lawrie, Stephen L Hoffman, Adrian V S Hill
Published 2013-01-01

Safety, Immunogenicity and Efficacy of Prime-Boost Vaccination with ChAd63 and MVA Encoding ME-TRAP against Plasmodium falciparum Infection in Adults in Senegal.

by Victorine A Mensah, Aly Gueye, Magatte Ndiaye, Nick J Edwards, Danny Wright, Nicholas A Anagnostou, Massamba Syll, Amy Ndaw, Annie Abiola, Carly Bliss, Jules-François Gomis, Ines Petersen, Caroline Ogwang, Tandakha Dieye, Nicola K Viebig, Alison M Lawrie, Rachel Roberts, Alfredo Nicosia, Babacar Faye, Oumar Gaye, Odile Leroy, Egeruan B Imoukhuede, Katie J Ewer, Philip Bejon, Adrian V S Hill, Badara Cisse, MVVC group
Published 2016-01-01

Safety and Immunogenicity of ChAd63/MVA Pfs25-IMX313 in a Phase I First-in-Human Trial

by Hans de Graaf, Ruth O. Payne, Iona Taylor, Kazutoyo Miura, Carol A. Long, Sean C. Elias, Marija Zaric, Angela M. Minassian, Sarah E. Silk, Lee Li, Ian D. Poulton, Megan Baker, Simon J. Draper, Diane Gbesemete, Nathan J. Brendish, Filipa Martins, Arianna Marini, David Mekhaiel, Nick J. Edwards, Rachel Roberts, Johan Vekemans, Sarah Moyle, Saul N. Faust, Eleanor Berrie, Alison M. Lawrie, Fergal Hill, Adrian V. S. Hill, Sumi Biswas
Published 2021-07-01

Phase Ia clinical evaluation of the safety and immunogenicity of the Plasmodium falciparum blood-stage antigen AMA1 in ChAd63 and MVA vaccine vectors.

by Susanne H Sheehy, Christopher J A Duncan, Sean C Elias, Sumi Biswas, Katharine A Collins, Geraldine A O'Hara, Fenella D Halstead, Katie J Ewer, Tabitha Mahungu, Alexandra J Spencer, Kazutoyo Miura, Ian D Poulton, Matthew D J Dicks, Nick J Edwards, Eleanor Berrie, Sarah Moyle, Stefano Colloca, Riccardo Cortese, Katherine Gantlett, Carole A Long, Alison M Lawrie, Sarah C Gilbert, Tom Doherty, Alfredo Nicosia, Adrian V S Hill, Simon J Draper
Published 2012-01-01

Safety and Immunogenicity of Malaria Vectored Vaccines Given with Routine Expanded Program on Immunization Vaccines in Gambian Infants and Neonates: A Randomized Controlled Trial

by Victorine A. Mensah, Sophie Roetynck, Ebrima K. Kanteh, Georgina Bowyer, Amy Ndaw, Francis Oko, Carly M. Bliss, Ya Jankey Jagne, Riccardo Cortese, Alfredo Nicosia, Alfredo Nicosia, Alfredo Nicosia, Rachel Roberts, Flavia D’Alessio, Odile Leroy, Babacar Faye, Beate Kampmann, Beate Kampmann, Badara Cisse, Kalifa Bojang, Stephen Gerry, Nicola K. Viebig, Alison M. Lawrie, Ed Clarke, Egeruan B. Imoukhuede, Katie J. Ewer, Adrian V. S. Hill, Adrian V. S. Hill, Muhammed O. Afolabi
Published 2017-11-01

Impact on malaria parasite multiplication rates in infected volunteers of the protein-in-adjuvant vaccine AMA1-C1/Alhydrogel+CPG 7909.

by Christopher J A Duncan, Susanne H Sheehy, Katie J Ewer, Alexander D Douglas, Katharine A Collins, Fenella D Halstead, Sean C Elias, Patrick J Lillie, Kelly Rausch, Joan Aebig, Kazutoyo Miura, Nick J Edwards, Ian D Poulton, Angela Hunt-Cooke, David W Porter, Fiona M Thompson, Ros Rowland, Simon J Draper, Sarah C Gilbert, Michael P Fay, Carole A Long, Daming Zhu, Yimin Wu, Laura B Martin, Charles F Anderson, Alison M Lawrie, Adrian V S Hill, Ruth D Ellis
Published 2011-01-01

Safety and immunogenicity of heterologous prime-boost immunisation with Plasmodium falciparum malaria candidate vaccines, ChAd63 ME-TRAP and MVA ME-TRAP, in healthy Gambian and Ken...

by Caroline Ogwang, Muhammed Afolabi, Domtila Kimani, Ya Jankey Jagne, Susanne H Sheehy, Carly M Bliss, Christopher J A Duncan, Katharine A Collins, Miguel A Garcia Knight, Eva Kimani, Nicholas A Anagnostou, Eleanor Berrie, Sarah Moyle, Sarah C Gilbert, Alexandra J Spencer, Peninah Soipei, Jenny Mueller, Joseph Okebe, Stefano Colloca, Riccardo Cortese, Nicola K Viebig, Rachel Roberts, Katherine Gantlett, Alison M Lawrie, Alfredo Nicosia, Egeruan B Imoukhuede, Philip Bejon, Britta C Urban, Katie L Flanagan, Katie J Ewer, Roma Chilengi, Adrian V S Hill, Kalifa Bojang
Published 2013-01-01