Methods for Measuring T-Cell Memory to Vaccination: From Mouse to Man

by Amy Flaxman, Katie J. Ewer
Published 2018-07-01

Development of an in vitro assay and demonstration of Plasmodium berghei liver-stage inhibition by TRAP-specific CD8+ T cells.

by Rhea J Longley, Karolis Bauza, Katie J Ewer, Adrian V S Hill, Alexandra J Spencer
Published 2015-01-01

Identification of Immunodominant Responses to the Plasmodium falciparum Antigens PfUIS3, PfLSA1 and PfLSAP2 in Multiple Strains of Mice.

by Rhea J Longley, Benedict R Halbroth, Katie J Ewer, Adrian V S Hill, Alexandra J Spencer
Published 2015-01-01

Activation-induced Markers Detect Vaccine-Specific CD4+ T Cell Responses Not Measured by Assays Conventionally Used in Clinical Trials

by Georgina Bowyer, Tommy Rampling, Jonathan Powlson, Richard Morter, Daniel Wright, Adrian V.S. Hill, Katie J. Ewer
Published 2018-07-01

CXCR3+ T Follicular Helper Cells Induced by Co-Administration of RTS,S/AS01B and Viral-Vectored Vaccines Are Associated With Reduced Immunogenicity and Efficacy Against Malaria

by Georgina Bowyer, Amy Grobbelaar, Tommy Rampling, Navin Venkatraman, Danielle Morelle, Ripley W. Ballou, Adrian V. S. Hill, Katie J. Ewer
Published 2018-07-01

Characterization of Antigenic MHC-Class-I-Restricted T Cell Epitopes in the Glycoprotein of Ebolavirus

by Jonathan Powlson, Daniel Wright, Antra Zeltina, Mark Giza, Morten Nielsen, Tommy Rampling, Navin Venkatrakaman, Thomas A. Bowden, Adrian V.S. Hill, Katie J. Ewer
Published 2019-11-01

A phase Ia study to assess the safety and immunogenicity of new malaria vaccine candidates ChAd63 CS administered alone and with MVA CS.

by Eoghan de Barra, Susanne H Hodgson, Katie J Ewer, Carly M Bliss, Kerrie Hennigan, Ann Collins, Eleanor Berrie, Alison M Lawrie, Sarah C Gilbert, Alfredo Nicosia, Samuel J McConkey, Adrian V S Hill
Published 2014-01-01

Safety and Immunogenicity of a Novel Recombinant Simian Adenovirus ChAdOx2 as a Vectored Vaccine

by Pedro M. Folegatti, Duncan Bellamy, Rachel Roberts, Jonathan Powlson, Nick J. Edwards, Catherine F. Mair, Georgina Bowyer, Ian Poulton, Celia H. Mitton, Nicky Green, Eleanor Berrie, Alison M. Lawrie, Adrian V.S. Hill, Katie J. Ewer, John Hermon-Taylor, Sarah C. Gilbert
Published 2019-05-01

Safety and Immunogenicity of the Heterosubtypic Influenza A Vaccine MVA-NP+M1 Manufactured on the AGE1.CR.pIX Avian Cell Line

by Pedro M. Folegatti, Duncan Bellamy, Amy Flaxman, Catherine Mair, Chris Ellis, Raquel L. Ramon, Fernando Ramos Lopez, Celia Mitton, Megan Baker, Ian Poulton, Alison Lawrie, Rachel Roberts, Angela Minassian, Katie J. Ewer, Thomas G. Evans, Adrian V. S. Hill, Sarah C. Gilbert
Published 2019-03-01

Safety and Immunogenicity of Adenovirus and Poxvirus Vectored Vaccines against a Mycobacterium Avium Complex Subspecies

by Pedro M. Folegatti, Amy Flaxman, Daniel Jenkin, Rebecca Makinson, Lucy Kingham-Page, Duncan Bellamy, Fernando Ramos Lopez, Jonathan Sheridan, Ian Poulton, Jeremy Aboagye, Nguyen Tran, Celia Mitton, Rachel Roberts, Alison M. Lawrie, Adrian V. S. Hill, Katie J. Ewer, Sarah Gilbert
Published 2021-03-01

Assessment of humoral immune responses to blood-stage malaria antigens following ChAd63-MVA immunization, controlled human malaria infection and natural exposure.

by Sumi Biswas, Prateek Choudhary, Sean C Elias, Kazutoyo Miura, Kathryn H Milne, Simone C de Cassan, Katharine A Collins, Fenella D Halstead, Carly M Bliss, Katie J Ewer, Faith H Osier, Susanne H Hodgson, Christopher J A Duncan, Geraldine A O'Hara, Carole A Long, Adrian V S Hill, Simon J Draper
Published 2014-01-01

A single dose of ChAdOx1 Chik vaccine induces neutralizing antibodies against four chikungunya virus lineages in a phase 1 clinical trial

by Pedro M. Folegatti, Kate Harrison, Lorena Preciado-Llanes, Fernando Ramos Lopez, Mustapha Bittaye, Young Chan Kim, Amy Flaxman, Duncan Bellamy, Rebecca Makinson, Jonathan Sheridan, Sasha R. Azar, Rafael Kroon Campos, Mark Tilley, Nguyen Tran, Daniel Jenkin, Ian Poulton, Alison Lawrie, Rachel Roberts, Eleanor Berrie, Shannan L. Rossi, Adrian Hill, Katie J. Ewer, Arturo Reyes-Sandoval
Published 2021-07-01

First field efficacy trial of the ChAd63 MVA ME-TRAP vectored malaria vaccine candidate in 5-17 months old infants and children.

by Alfred B Tiono, Issa Nébié, Nicholas Anagnostou, Aboubacar S Coulibaly, Georgina Bowyer, Erika Lam, Edith C Bougouma, Alphonse Ouedraogo, Jean Baptist B Yaro, Aïssata Barry, Rachel Roberts, Tommy Rampling, Carly Bliss, Susanne Hodgson, Alison Lawrie, Amidou Ouedraogo, Egeruan Babatunde Imoukhuede, Katie J Ewer, Nicola K Viebig, Amidou Diarra, Odile Leroy, Philip Bejon, Adrian V S Hill, Sodiomon B Sirima
Published 2018-01-01

Safety, Immunogenicity and Efficacy of Prime-Boost Vaccination with ChAd63 and MVA Encoding ME-TRAP against Plasmodium falciparum Infection in Adults in Senegal.

by Victorine A Mensah, Aly Gueye, Magatte Ndiaye, Nick J Edwards, Danny Wright, Nicholas A Anagnostou, Massamba Syll, Amy Ndaw, Annie Abiola, Carly Bliss, Jules-François Gomis, Ines Petersen, Caroline Ogwang, Tandakha Dieye, Nicola K Viebig, Alison M Lawrie, Rachel Roberts, Alfredo Nicosia, Babacar Faye, Oumar Gaye, Odile Leroy, Egeruan B Imoukhuede, Katie J Ewer, Philip Bejon, Adrian V S Hill, Badara Cisse, MVVC group
Published 2016-01-01

Phase Ia clinical evaluation of the safety and immunogenicity of the Plasmodium falciparum blood-stage antigen AMA1 in ChAd63 and MVA vaccine vectors.

by Susanne H Sheehy, Christopher J A Duncan, Sean C Elias, Sumi Biswas, Katharine A Collins, Geraldine A O'Hara, Fenella D Halstead, Katie J Ewer, Tabitha Mahungu, Alexandra J Spencer, Kazutoyo Miura, Ian D Poulton, Matthew D J Dicks, Nick J Edwards, Eleanor Berrie, Sarah Moyle, Stefano Colloca, Riccardo Cortese, Katherine Gantlett, Carole A Long, Alison M Lawrie, Sarah C Gilbert, Tom Doherty, Alfredo Nicosia, Adrian V S Hill, Simon J Draper
Published 2012-01-01

Safety and Immunogenicity of Malaria Vectored Vaccines Given with Routine Expanded Program on Immunization Vaccines in Gambian Infants and Neonates: A Randomized Controlled Trial

by Victorine A. Mensah, Sophie Roetynck, Ebrima K. Kanteh, Georgina Bowyer, Amy Ndaw, Francis Oko, Carly M. Bliss, Ya Jankey Jagne, Riccardo Cortese, Alfredo Nicosia, Alfredo Nicosia, Alfredo Nicosia, Rachel Roberts, Flavia D’Alessio, Odile Leroy, Babacar Faye, Beate Kampmann, Beate Kampmann, Badara Cisse, Kalifa Bojang, Stephen Gerry, Nicola K. Viebig, Alison M. Lawrie, Ed Clarke, Egeruan B. Imoukhuede, Katie J. Ewer, Adrian V. S. Hill, Adrian V. S. Hill, Muhammed O. Afolabi
Published 2017-11-01

Impact on malaria parasite multiplication rates in infected volunteers of the protein-in-adjuvant vaccine AMA1-C1/Alhydrogel+CPG 7909.

by Christopher J A Duncan, Susanne H Sheehy, Katie J Ewer, Alexander D Douglas, Katharine A Collins, Fenella D Halstead, Sean C Elias, Patrick J Lillie, Kelly Rausch, Joan Aebig, Kazutoyo Miura, Nick J Edwards, Ian D Poulton, Angela Hunt-Cooke, David W Porter, Fiona M Thompson, Ros Rowland, Simon J Draper, Sarah C Gilbert, Michael P Fay, Carole A Long, Daming Zhu, Yimin Wu, Laura B Martin, Charles F Anderson, Alison M Lawrie, Adrian V S Hill, Ruth D Ellis
Published 2011-01-01

Safety and immunogenicity of heterologous prime-boost immunisation with Plasmodium falciparum malaria candidate vaccines, ChAd63 ME-TRAP and MVA ME-TRAP, in healthy Gambian and Ken...

by Caroline Ogwang, Muhammed Afolabi, Domtila Kimani, Ya Jankey Jagne, Susanne H Sheehy, Carly M Bliss, Christopher J A Duncan, Katharine A Collins, Miguel A Garcia Knight, Eva Kimani, Nicholas A Anagnostou, Eleanor Berrie, Sarah Moyle, Sarah C Gilbert, Alexandra J Spencer, Peninah Soipei, Jenny Mueller, Joseph Okebe, Stefano Colloca, Riccardo Cortese, Nicola K Viebig, Rachel Roberts, Katherine Gantlett, Alison M Lawrie, Alfredo Nicosia, Egeruan B Imoukhuede, Philip Bejon, Britta C Urban, Katie L Flanagan, Katie J Ewer, Roma Chilengi, Adrian V S Hill, Kalifa Bojang
Published 2013-01-01