Blockade of an innate immune amplifier to fight immune hyperactivation in COVID-19?

by Alexandra K. Kiemer
Published 2020-11-01

M2 polarization enhances silica nanoparticle uptake by macrophages

by Jessica eHoppstädter, Michelle eSeif, Anna eDembek, Christian eCavelius, Hanno eHuwer, Annette eKraegeloh, Alexandra K Kiemer
Published 2015-03-01

Toll-Like Receptor 2 Release by Macrophages: An Anti-inflammatory Program Induced by Glucocorticoids and Lipopolysaccharide

by Jessica Hoppstädter, Anna Dembek, Rebecca Linnenberger, Charlotte Dahlem, Ahmad Barghash, Claudia Fecher-Trost, Gregor Fuhrmann, Marcus Koch, Annette Kraegeloh, Hanno Huwer, Alexandra K. Kiemer
Published 2019-07-01

Myxobacteria-Derived Outer Membrane Vesicles: Potential Applicability Against Intracellular Infections

by Adriely Goes, Philipp Lapuhs, Thomas Kuhn, Eilien Schulz, Robert Richter, Fabian Panter, Charlotte Dahlem, Marcus Koch, Ronald Garcia, Alexandra K. Kiemer, Rolf Müller, Gregor Fuhrmann
Published 2020-01-01

Baikalomycins A-C, New Aquayamycin-Type Angucyclines Isolated from Lake Baikal Derived <i>Streptomyces</i> sp. IB201691-2A

by Irina Voitsekhovskaia, Constanze Paulus, Charlotte Dahlem, Yuriy Rebets, Suvd Nadmid, Josef Zapp, Denis Axenov-Gribanov, Christian Rückert, Maxim Timofeyev, Jörn Kalinowski, Alexandra K. Kiemer, Andriy Luzhetskyy
Published 2020-05-01

Hepatocellular Carcinoma and Nuclear Paraspeckles: Induction in Chemoresistance and Prediction for Poor Survival

by Sonja M. Kessler, Kevan Hosseini, Usama Khamis Hussein, Kyoung Min Kim, Markus List, Christina S. Schultheiß, Marcel H. Schulz, Stephan Laggai, Kyu Yun Jang, Alexandra K. Kiemer
Published 2019-04-01

Susceptibility of Different Mouse Wild Type Strains to Develop Diet-Induced NAFLD/AFLD-Associated Liver Disease.

by Vera H I Fengler, Tanja Macheiner, Sonja M Kessler, Beate Czepukojc, Katja Gemperlein, Rolf Müller, Alexandra K Kiemer, Christoph Magnes, Johannes Haybaeck, Carolin Lackner, Karine Sargsyan
Published 2016-01-01

The IGF2 mRNA binding protein p62/IGF2BP2-2 induces fatty acid elongation as a critical feature of steatosis[S]

by Stephan Laggai, Sonja M. Kessler, Stefan Boettcher, Valérie Lebrun, Katja Gemperlein, Eva Lederer, Isabelle A. Leclercq, Rolf Mueller, Rolf W. Hartmann, Johannes Haybaeck, Alexandra K. Kiemer
Published 2014-06-01

Amplified Host Defense by Toll-Like Receptor-Mediated Downregulation of the Glucocorticoid-Induced Leucine Zipper (GILZ) in Macrophages

by Jessica Hoppstädter, Britta Diesel, Rebecca Linnenberger, Nina Hachenthal, Sara Flamini, Marie Minet, Petra Leidinger, Christina Backes, Friedrich Grässer, Eckart Meese, Stefano Bruscoli, Carlo Riccardi, Hanno Huwer, Alexandra K. Kiemer
Published 2019-01-01

Thioholgamide A, a New Anti-Proliferative Anti-Tumor Agent, Modulates Macrophage Polarization and Metabolism

by Charlotte Dahlem, Wei Xiong Siow, Maria Lopatniuk, William K. F. Tse, Sonja M. Kessler, Susanne H. Kirsch, Jessica Hoppstädter, Angelika M. Vollmar, Rolf Müller, Andriy Luzhetskyy, Karin Bartel, Alexandra K. Kiemer
Published 2020-05-01

The mRNA-binding Protein TTP/ZFP36 in Hepatocarcinogenesis and Hepatocellular Carcinoma

by Tarek Kröhler, Sonja M. Kessler, Kevan Hosseini, Markus List, Ahmad Barghash, Sonika Patial, Stephan Laggai, Katja Gemperlein, Johannes Haybaeck, Rolf Müller, Volkhard Helms, Marcel H. Schulz, Jessica Hoppstädter, Perry J. Blackshear, Alexandra K. Kiemer
Published 2019-11-01

Fatty Acid Elongation in Non-Alcoholic Steatohepatitis and Hepatocellular Carcinoma

by Sonja M. Kessler, Yvette Simon, Katja Gemperlein, Kathrin Gianmoena, Cristina Cadenas, Vincent Zimmer, Juliane Pokorny, Ahmad Barghash, Volkhard Helms, Nico van Rooijen, Rainer M. Bohle, Frank Lammert, Jan G. Hengstler, Rolf Mueller, Johannes Haybaeck, Alexandra K. Kiemer
Published 2014-04-01

Dysregulation of cholesterol homeostasis in human lung cancer tissue and tumour-associated macrophages

by Jessica Hoppstädter, Anna Dembek, Marcus Höring, Hanna S. Schymik, Charlotte Dahlem, Afnan Sultan, Natalie Wirth, Salma Al-Fityan, Britta Diesel, Gilles Gasparoni, Jörn Walter, Volkhard Helms, Hanno Huwer, Martin Simon, Gerhard Liebisch, Marcel H. Schulz, Alexandra K. Kiemer
Published 2021-10-01

Transient hepatic overexpression of Insulin-like growth factor 2 induces free cholesterol and lipid droplet formation

by Sonja M Kessler, Stephan eLaggai, Elien evan Wonterghem, Elien evan Wonterghem, Katja eGemperlein, Rolf eMüller, Johannes eHaybaeck, Roosmarijn E Vandenbroucke, Roosmarijn E Vandenbroucke, Manfred eOgris, Claude eLibert, Claude eLibert, Alexandra K Kiemer
Published 2016-04-01

The long non-coding RNA H19 suppresses carcinogenesis and chemoresistance in hepatocellular carcinoma

by Christina S. Schultheiss, Stephan Laggai, Beate Czepukojc, Usama K. Hussein, Markus List, Ahmad Barghash, Sascha Tierling, Kevan Hosseini, Nicole Golob-Schwarzl, Juliane Pokorny, Nina Hachenthal, Marcel Schulz, Volkhard Helms, Jörn Walter, Vincent Zimmer, Frank Lammert, Rainer M. Bohle, Luisa Dandolo, Johannes Haybaeck, Alexandra K. Kiemer, Sonja M. Kessler
Published 2017-08-01

CRUP: a comprehensive framework to predict condition-specific regulatory units

by Anna Ramisch, Verena Heinrich, Laura V. Glaser, Alisa Fuchs, Xinyi Yang, Philipp Benner, Robert Schöpflin, Na Li, Sarah Kinkley, Anja Römer-Hillmann, John Longinotto, Steffen Heyne, Beate Czepukojc, Sonja M. Kessler, Alexandra K. Kiemer, Cristina Cadenas, Laura Arrigoni, Nina Gasparoni, Thomas Manke, Thomas Pap, John A. Pospisilik, Jan Hengstler, Jörn Walter, Sebastiaan H. Meijsing, Ho-Ryun Chung, Martin Vingron
Published 2019-11-01

IGF2 mRNA Binding Protein 2 Transgenic Mice Are More Prone to Develop a Ductular Reaction and to Progress Toward Cirrhosis

by Beate Czepukojc, Ali Abuhaliema, Ahmad Barghash, Ahmad Barghash, Sascha Tierling, Norbert Naß, Yvette Simon, Christina Körbel, Cristina Cadenas, Noemi van Hul, Noemi van Hul, Agapios Sachinidis, Jan G. Hengstler, Volkhard Helms, Matthias W. Laschke, Jörn Walter, Johannes Haybaeck, Johannes Haybaeck, Johannes Haybaeck, Isabelle Leclercq, Alexandra K. Kiemer, Sonja M. Kessler, Sonja M. Kessler, Sonja M. Kessler
Published 2019-09-01

High Keratin 8/18 Ratio Predicts Aggressive Hepatocellular Cancer Phenotype

by Nicole Golob-Schwarzl, Kira Bettermann, Anita Kuldeep Mehta, Sonja M. Kessler, Julia Unterluggauer, Stefanie Krassnig, Kensuke Kojima, Xintong Chen, Yujin Hoshida, Nabeel M. Bardeesy, Heimo Müller, Vendula Svendova, Michael G. Schimek, Clemens Diwoky, Alexandra Lipfert, Vineet Mahajan, Cornelia Stumptner, Andrea Thüringer, Leopold F. Fröhlich, Tatjana Stojakovic, K.P.R. Nilsson, Thomas Kolbe, Thomas Rülicke, Thomas M. Magin, Pavel Strnad, Alexandra K. Kiemer, Richard Moriggl, Johannes Haybaeck
Published 2019-02-01