Changes in nano-mechanical properties of human epidermal cornified cells in children with atopic dermatitis [version 2; peer review: 2 approved]

by Marek Haftek, Maeve A McAleer, Ivone Jakasa, WH Irwin McLean, Sanja Kezic, Alan D. Irvine
Published 2020-07-01

Efficacy of Sirolimus in Patients Requiring Tracheostomy for Life-Threatening Lymphatic Malformation of the Head and Neck: A Report From the European Reference Network

by Annegret Holm, Annegret Holm, Maroeska te Loo, Maroeska te Loo, Leo Schultze Kool, Leo Schultze Kool, Päivi Salminen, Päivi Salminen, Veronica Celis, Eulalia Baselga, Sophie Duignan, Sophie Duignan, Sophie Duignan, Sophie Duignan, Veronika Dvorakova, Veronika Dvorakova, Veronika Dvorakova, Veronika Dvorakova, Alan D. Irvine, Alan D. Irvine, Alan D. Irvine, Alan D. Irvine, Laurence M. Boon, Laurence M. Boon, Miikka Vikkula, Miikka Vikkula, Miikka Vikkula, Nader Ghaffarpour, Nader Ghaffarpour, Charlotte M. Niemeyer, Charlotte M. Niemeyer, Jochen Rössler, Jochen Rössler, Jochen Rössler, Friedrich G. Kapp, Friedrich G. Kapp
Published 2021-09-01

Adhesion of Staphylococcus aureus to Corneocytes from Atopic Dermatitis Patients Is Controlled by Natural Moisturizing Factor Levels

by Cécile Feuillie, Pauline Vitry, Maeve A. McAleer, Sanja Kezic, Alan D. Irvine, Joan A. Geoghegan, Yves F. Dufrêne
Published 2018-08-01

Inhaled methoxyflurane (Penthrox®) versus placebo for injury-associated analgesia in children—the MAGPIE trial (MEOF-002): study protocol for a randomised controlled trial

by Stuart Hartshorn, Michael J. Barrett, Mark D. Lyttle, Sue Anne Yee, Alan T. Irvine, in collaboration with Paediatric Emergency Research in the UK and Ireland (PERUKI)
Published 2019-07-01

Clinical experience with the AKT1 inhibitor miransertib in two children with PIK3CA-related overgrowth syndrome

by Karina Forde, Nicoletta Resta, Carlotta Ranieri, David Rea, Olga Kubassova, Mark Hinton, Katrina A. Andrews, Robert Semple, Alan D. Irvine, Veronika Dvorakova
Published 2021-02-01

Protocol for a prospective, observational, longitudinal study in paediatric patients with moderate-to-severe atopic dermatitis (PEDISTAD): study objectives, design and methodology

by Alan D Irvine, Amy S Paller, Emma Guttman-Yassky, Eulalia Baselga, Marjolein de Bruin-Weller, Shyamalie Jayawardena, Annie Zhang, Paola Mina-Osorio, Elena Rizova, Zafer E Ozturk
Published 2020-03-01

Dupilumab Provides Significant Clinical Benefit in a Phase 3 Trial in Adolescents with Uncontrolled Atopic Dermatitis Irrespective of Prior Systemic Immunosuppressant Use

by Mette Deleuran, Danielle Marcoux, Marjolein S. Bruin-Weller, Alan D. Irvine, Eulalia Baselga, Kangmo Ahn, Ana Paula Castro, Ashish Bansal, Jingdong Chao, Gaëlle Bégo-Le-Bagousse, Ana B. Rossi
Published 2021-07-01

Carrier status for the common R501X and 2282del4 filaggrin mutations is not associated with hearing phenotypes in 5,377 children from the ALSPAC cohort.

by Santiago Rodriguez, Amanda J Hall, Raquel Granell, W H Irwin McLean, Alan D Irvine, Colin N A Palmer, George Davey Smith, John Henderson, Ian N M Day
Published 2009-06-01

Development of allele-specific therapeutic siRNA in Meesmann epithelial corneal dystrophy.

by Haihui Liao, Alan D Irvine, Caroline J Macewen, Kathryn H Weed, Louise Porter, Laura D Corden, A Bethany Gibson, Jonathan E Moore, Frances J D Smith, W H Irwin McLean, C B Tara Moore
Published 2011-01-01

Meta-Analysis of Mutations in <i>ALOX12B</i> or <i>ALOXE3</i> Identified in a Large Cohort of 224 Patients

by Alrun Hotz, Julia Kopp, Emmanuelle Bourrat, Vinzenz Oji, Katalin Komlosi, Kathrin Giehl, Bakar Bouadjar, Anette Bygum, Iliana Tantcheva-Poor, Maritta Hellström Pigg, Cristina Has, Zhou Yang, Alan D. Irvine, Regina C. Betz, Giovanna Zambruno, Gianluca Tadini, Kira Süßmuth, Robert Gruber, Matthias Schmuth, Juliette Mazereeuw-Hautier, Natalie Jonca, Sophie Guez, Michela Brena, Angela Hernandez-Martin, Peter van den Akker, Maria C. Bolling, Katariina Hannula-Jouppi, Andreas D. Zimmer, Svenja Alter, Anders Vahlquist, Judith Fischer
Published 2021-01-01