Why do mutant allele frequencies in oncogenes peak around .40 and rapidly decrease?

by Kasthuri Kannan, Adriana Heguy
Published 2016-01-01

Calorie Restriction Suppresses Age-Dependent Hippocampal Transcriptional Signatures.

by Marissa J Schafer, Igor Dolgalev, Melissa J Alldred, Adriana Heguy, Stephen D Ginsberg
Published 2015-01-01

Bacteriophages as potential new mammalian pathogens

by George V. Tetz, Kelly V. Ruggles, Hua Zhou, Adriana Heguy, Aristotelis Tsirigos, Victor Tetz
Published 2017-08-01

Abundance of Plant-Associated <i>Gammaproteobacteria</i> Correlates with Immunostimulatory Activity of <i>Angelica sinensis</i>

by Kriti Kalpana, Diego Montenegro, Giovanna Romero, Ximena Peralta, Betul Akgol Oksuz, Adriana Heguy, Moriya Tsuji, Akira Kawamura
Published 2019-05-01

Nascent Induced Pluripotent Stem Cells Efficiently Generate Entirely iPSC-Derived Mice while Expressing Differentiation-Associated Genes

by Bhishma Amlani, Yiyuan Liu, Taotao Chen, Ly-Sha Ee, Peter Lopez, Adriana Heguy, Effie Apostolou, Sang Yong Kim, Matthias Stadtfeld
Published 2018-01-01

Functional genomic analysis identifies indoxyl sulfate as a major, poorly dialyzable uremic toxin in end-stage renal disease.

by Sachin Jhawar, Prabhjot Singh, Daniel Torres, Francisco Ramirez-Valle, Hania Kassem, Trina Banerjee, Igor Dolgalev, Adriana Heguy, Jiri Zavadil, Jerome Lowenstein
Published 2015-01-01

Genome-Wide DNA Methylation Profiles in Community Members Exposed to the World Trade Center Disaster

by Alan A. Arslan, Stephanie Tuminello, Lei Yang, Yian Zhang, Nedim Durmus, Matija Snuderl, Adriana Heguy, Anne Zeleniuch-Jacquotte, Yongzhao Shao, Joan Reibman
Published 2020-07-01

Apolipoprotein L1 risk variants associate with prevalent atherosclerotic disease in African American systemic lupus erythematosus patients.

by Ashira Blazer, Binhuan Wang, Danny Simpson, Tomas Kirchhoff, Sean Heffron, Robert M Clancy, Adriana Heguy, Karina Ray, Matija Snuderl, Jill P Buyon
Published 2017-01-01

Axon TRAP reveals learning-associated alterations in cortical axonal mRNAs in the lateral amygdala

by Linnaea E Ostroff, Emanuela Santini, Robert Sears, Zachary Deane, Rahul N Kanadia, Joseph E LeDoux, Tenzin Lhakhang, Aristotelis Tsirigos, Adriana Heguy, Eric Klann
Published 2019-12-01

The fecal, oral, and skin microbiota of children with Chagas disease treated with benznidazole.

by Carlos Robello, Doris Patricia Maldonado, Anna Hevia, Marina Hoashi, Paola Frattaroli, Valentina Montacutti, Adriana Heguy, Igor Dolgalev, Maricruz Mojica, Gregorio Iraola, Maria G Dominguez-Bello
Published 2019-01-01

Correction: The fecal, oral, and skin microbiota of children with Chagas disease treated with benznidazole.

by Carlos Robello, Doris Patricia Maldonado, Anna Hevia, Marina Hoashi, Paola Frattaroli, Valentina Montacutti, Adriana Heguy, Igor Dolgalev, Maricruz Mojica, Gregorio Iraola, Maria G Dominguez-Bello
Published 2019-01-01

Transcriptomic Coupling of PKP2 With Inflammatory and Immune Pathways Endogenous to Adult Cardiac Myocytes

by Marta Pérez-Hernández, Grecia M. Marrón-Liñares, Florencia Schlamp, Adriana Heguy, Chantal J. M. van Opbergen, Valeria Mezzano, Mingliang Zhang, Feng-Xia Liang, Marina Cerrone, Mario Delmar
Published 2021-01-01

Dispersal dynamics of SARS-CoV-2 lineages during the first epidemic wave in New York City.

by Simon Dellicour, Samuel L Hong, Bram Vrancken, Antoine Chaillon, Mandev S Gill, Matthew T Maurano, Sitharam Ramaswami, Paul Zappile, Christian Marier, Gordon W Harkins, Guy Baele, Ralf Duerr, Adriana Heguy
Published 2021-05-01

Development of a Versatile, Near Full Genome Amplification and Sequencing Approach for a Broad Variety of HIV-1 Group M Variants

by Andrew N. Banin, Michael Tuen, Jude S. Bimela, Marcel Tongo, Paul Zappile, Alireza Khodadadi-Jamayran, Aubin J. Nanfack, Josephine Meli, Xiaohong Wang, Dora Mbanya, Jeanne Ngogang, Adriana Heguy, Phillipe N. Nyambi, Charles Fokunang, Ralf Duerr
Published 2019-04-01

Staphylococcus aureus Responds to the Central Metabolite Pyruvate To Regulate Virulence

by Lamia Harper, Divya Balasubramanian, Elizabeth A. Ohneck, William E. Sause, Jessica Chapman, Bryan Mejia-Sosa, Tenzin Lhakhang, Adriana Heguy, Aristotelis Tsirigos, Beatrix Ueberheide, Jeffrey M. Boyd, Desmond S. Lun, Victor J. Torres, Anthony R. Richardson, Paul Dunman
Published 2018-01-01

Transposon insertion profiling by sequencing (TIPseq) for mapping LINE-1 insertions in the human genome

by Jared P. Steranka, Zuojian Tang, Mark Grivainis, Cheng Ran Lisa Huang, Lindsay M. Payer, Fernanda O. R. Rego, Thiago Luiz Araujo Miller, Pedro A. F. Galante, Sitharam Ramaswami, Adriana Heguy, David Fenyö, Jef D. Boeke, Kathleen H. Burns
Published 2019-03-01

Platelet Transcriptome Profiling in HIV and ATP-Binding Cassette Subfamily C Member 4 (ABCC4) as a Mediator of Platelet Activity

by Emanuela Marcantoni, PhD, Nicole Allen, BS, Matthew R. Cambria, BA, Rebecca Dann, BS, Michael Cammer, BS, Tenzin Lhakhang, BS, Meagan P. O’Brien, MD, Benjamin Kim, BS, Tilla Worgall, MD, PhD, Adriana Heguy, PhD, Aristotelis Tsirigos, PhD, Jeffrey S. Berger, MD, MS
Published 2018-02-01

Atrx inactivation drives disease-defining phenotypes in glioma cells of origin through global epigenomic remodeling

by Carla Danussi, Promita Bose, Prasanna T. Parthasarathy, Pedro C. Silberman, John S. Van Arnam, Mark Vitucci, Oliver Y. Tang, Adriana Heguy, Yuxiang Wang, Timothy A. Chan, Gregory J. Riggins, Erik P. Sulman, Frederick Lang, Chad J. Creighton, Benjamin Deneen, C. Ryan Miller, David J. Picketts, Kasthuri Kannan, Jason T. Huse
Published 2018-03-01

Genetic variation in DNA repair pathways and risk of non-Hodgkin's lymphoma.

by Justin Rendleman, Yevgeniy Antipin, Boris Reva, Christina Adaniel, Jennifer A Przybylo, Ana Dutra-Clarke, Nichole Hansen, Adriana Heguy, Kety Huberman, Laetitia Borsu, Ora Paltiel, Dina Ben-Yehuda, Jennifer R Brown, Arnold S Freedman, Chris Sander, Andrew Zelenetz, Robert J Klein, Yongzhao Shao, Mortimer Lacher, Joseph Vijai, Kenneth Offit, Tomas Kirchhoff
Published 2014-01-01

Molecular features of premenopausal breast cancers in Latin American women: Pilot results from the PRECAMA study.

by Magali Olivier, Liacine Bouaoun, Stephanie Villar, Alexis Robitaille, Vincent Cahais, Adriana Heguy, Graham Byrnes, Florence Le Calvez-Kelm, Gabriela Torres-Mejía, Isabel Alvarado-Cabrero, Fazlollah Shahram Imani-Razavi, Gloria Inés Sánchez, Roberto Jaramillo, Carolina Porras, Ana Cecilia Rodriguez, Maria Luisa Garmendia, José Luis Soto, Isabelle Romieu, Peggy Porter, Jamie Guenthoer, Sabina Rinaldi, PRECAMA team
Published 2019-01-01