Coexisting FGFR3 p.K650T mutation in two FGFR3-TACC3 fusion glioma cases

by Leomar Y. Ballester, Soheil Zorofchian Moghadamtousi, Norman E. Leeds, Jason T. Huse, Gregory N. Fuller
Published 2019-04-01

miR-34a repression in proneural malignant gliomas upregulates expression of its target PDGFRA and promotes tumorigenesis.

by Joachim Silber, Anders Jacobsen, Tatsuya Ozawa, Girish Harinath, Alicia Pedraza, Chris Sander, Eric C Holland, Jason T Huse
Published 2012-01-01

Spatial Distance Correlates With Genetic Distance in Diffuse Glioma

by Evan D. H. Gates, Evan D. H. Gates, Jie Yang, Jie Yang, Kazutaka Fukumura, Jonathan S. Lin, Jonathan S. Lin, Jonathan S. Lin, Jeffrey S. Weinberg, Sujit S. Prabhu, Lihong Long, David Fuentes, Erik P. Sulman, Jason T. Huse, Jason T. Huse, Dawid Schellingerhout
Published 2019-07-01

EGFR and PDGFRA co-expression and heterodimerization in glioblastoma tumor sphere lines

by Debyani Chakravarty, Alicia M. Pedraza, Jesse Cotari, Angela H. Liu, Diana Punko, Aushim Kokroo, Jason T. Huse, Gregoire Altan-Bonnet, Cameron W. Brennan
Published 2017-08-01

Recruited cells can become transformed and overtake PDGF-induced murine gliomas in vivo during tumor progression.

by Elena I Fomchenko, Joseph D Dougherty, Karim Y Helmy, Amanda M Katz, Alexander Pietras, Cameron Brennan, Jason T Huse, Ana Milosevic, Eric C Holland
Published 2011-01-01

Somatic genome editing with the RCAS-TVA-CRISPR-Cas9 system for precision tumor modeling

by Barbara Oldrini, Álvaro Curiel-García, Carolina Marques, Veronica Matia, Özge Uluçkan, Osvaldo Graña-Castro, Raul Torres-Ruiz, Sandra Rodriguez-Perales, Jason T. Huse, Massimo Squatrito
Published 2018-04-01

G-quadruplex DNA drives genomic instability and represents a targetable molecular abnormality in ATRX-deficient malignant glioma

by Yuxiang Wang, Jie Yang, Aaron T. Wild, Wei H. Wu, Rachna Shah, Carla Danussi, Gregory J. Riggins, Kasthuri Kannan, Erik P. Sulman, Timothy A. Chan, Jason T. Huse
Published 2019-02-01

A Cell Engineering Strategy to Enhance the Safety of Stem Cell Therapies

by Elisa Oricchio, Eirini P. Papapetrou, Fabien Lafaille, Yosif M. Ganat, Sonja Kriks, Ana Ortega-Molina, Willie H. Mark, Julie Teruya-Feldstein, Jason T. Huse, Victor Reuter, Michel Sadelain, Lorenz Studer, Hans-Guido Wendel
Published 2014-09-01

Involvement of miRNAs in the differentiation of human glioblastoma multiforme stem-like cells.

by Beatriz Aldaz, Ainara Sagardoy, Lorena Nogueira, Elizabeth Guruceaga, Lara Grande, Jason T Huse, Maria A Aznar, Ricardo Díez-Valle, Sonia Tejada-Solís, Marta M Alonso, Jose L Fernandez-Luna, Jose A Martinez-Climent, Raquel Malumbres
Published 2013-01-01

CD11c+CD163+ Cells and Signal Transducer and Activator of Transcription 3 (STAT3) Expression Are Common in Melanoma Leptomeningeal Disease

by Hinda Najem, Anantha Marisetty, Craig Horbinski, Craig Horbinski, James Long, Jason T. Huse, Isabella C. Glitza Oliva, Sherise D. Ferguson, Priya U. Kumthekar, Derek A. Wainwright, Peiwen Chen, Maciej S. Lesniak, Jared K. Burks, Amy B. Heimberger
Published 2021-10-01

Multicenter study demonstrates radiomic features derived from magnetic resonance perfusion images identify pseudoprogression in glioblastoma

by Nabil Elshafeey, Aikaterini Kotrotsou, Ahmed Hassan, Nancy Elshafei, Islam Hassan, Sara Ahmed, Srishti Abrol, Anand Agarwal, Kamel El Salek, Samuel Bergamaschi, Jay Acharya, Fanny E. Moron, Meng Law, Gregory N. Fuller, Jason T. Huse, Pascal O. Zinn, Rivka R. Colen
Published 2019-07-01

A phase I study of single-agent perifosine for recurrent or refractory pediatric CNS and solid tumors.

by Oren J Becher, Nathan E Millard, Shakeel Modak, Brian H Kushner, Sofia Haque, Ivan Spasojevic, Tanya M Trippett, Stephen W Gilheeney, Yasmin Khakoo, David C Lyden, Kevin C De Braganca, Jill M Kolesar, Jason T Huse, Kim Kramer, Nai-Kong V Cheung, Ira J Dunkel
Published 2017-01-01

Atrx inactivation drives disease-defining phenotypes in glioma cells of origin through global epigenomic remodeling

by Carla Danussi, Promita Bose, Prasanna T. Parthasarathy, Pedro C. Silberman, John S. Van Arnam, Mark Vitucci, Oliver Y. Tang, Adriana Heguy, Yuxiang Wang, Timothy A. Chan, Gregory J. Riggins, Erik P. Sulman, Frederick Lang, Chad J. Creighton, Benjamin Deneen, C. Ryan Miller, David J. Picketts, Kasthuri Kannan, Jason T. Huse
Published 2018-03-01

Profiling of patients with glioma reveals the dominant immunosuppressive axis is refractory to immune function restoration

by Martina Ott, Karl-Heinz Tomaszowski, Anantha Marisetty, Ling-Yuan Kong, Jun Wei, Maya Duna, Katia Blumberg, Xiaorong Ji, Carmen Jacobs, Gregory N. Fuller, Lauren A. Langford, Jason T. Huse, James P. Long, Jian Hu, Shulin Li, Jeffrey S. Weinberg, Sujit S. Prabhu, Raymond Sawaya, Sherise Ferguson, Ganesh Rao, Frederick F. Lang, Michael A. Curran, Amy B. Heimberger
Published 2020-09-01

Homozygous MTAP deletion in primary human glioblastoma is not associated with elevation of methylthioadenosine

by Yasaman Barekatain, Jeffrey J. Ackroyd, Victoria C. Yan, Sunada Khadka, Lin Wang, Ko-Chien Chen, Anton H. Poral, Theresa Tran, Dimitra K. Georgiou, Kenisha Arthur, Yu-Hsi Lin, Nikunj Satani, Elliot S. Ballato, Eliot I. Behr, Ana C. deCarvalho, Roel G. W. Verhaak, John de Groot, Jason T. Huse, John M. Asara, Raghu Kalluri, Florian L. Muller
Published 2021-07-01

Human Mesenchymal glioblastomas are characterized by an increased immune cell presence compared to Proneural and Classical tumors

by Ioannis Kaffes, Frank Szulzewsky, Zhihong Chen, Cameron J. Herting, Ben Gabanic, José E. Velázquez Vega, Jennifer Shelton, Jeffrey M. Switchenko, James L. Ross, Leon F. McSwain, Jason T. Huse, Bengt Westermark, Sven Nelander, Karin Forsberg-Nilsson, Lene Uhrbom, Naga Prathyusha Maturi, Patrick. J. Cimino, Eric C. Holland, Helmut Kettenmann, Cameron W. Brennan, Daniel J. Brat, Dolores Hambardzumyan
Published 2019-11-01

Glioblastoma stem cell-derived exosomes induce M2 macrophages and PD-L1 expression on human monocytes

by Konrad Gabrusiewicz, Xu Li, Jun Wei, Yuuri Hashimoto, Anantha L. Marisetty, Martina Ott, Fei Wang, David Hawke, John Yu, Luke M. Healy, Anwar Hossain, Johnny C. Akers, Sourindra N. Maiti, Shinji Yamashita, Yuzaburo Shimizu, Kenneth Dunner, M. Anna Zal, Jared K. Burks, Joy Gumin, Felix Nwajei, Aras Rezavanian, Shouhao Zhou, Ganesh Rao, Raymond Sawaya, Gregory N. Fuller, Jason T. Huse, Jack P. Antel, Shulin Li, Laurence Cooper, Erik P. Sulman, Clark Chen, Changiz Geula, Raghu Kalluri, Tomasz Zal, Amy B. Heimberger
Published 2018-04-01

Multiomics profiling of primary lung cancers and distant metastases reveals immunosuppression as a common characteristic of tumor cells with metastatic plasticity

by Won-Chul Lee, Alexandre Reuben, Xin Hu, Nicholas McGranahan, Runzhe Chen, Ali Jalali, Marcelo V. Negrao, Shawna M. Hubert, Chad Tang, Chia-Chin Wu, Anthony San Lucas, Whijae Roh, Kenichi Suda, Jihye Kim, Aik-Choon Tan, David H. Peng, Wei Lu, Ximing Tang, Chi-Wan Chow, Junya Fujimoto, Carmen Behrens, Neda Kalhor, Kazutaka Fukumura, Marcus Coyle, Rebecca Thornton, Curtis Gumbs, Jun Li, Chang-Jiun Wu, Latasha Little, Emily Roarty, Xingzhi Song, J. Jack Lee, Erik P. Sulman, Ganesh Rao, Stephen Swisher, Lixia Diao, Jing Wang, John V. Heymach, Jason T. Huse, Paul Scheet, Ignacio I. Wistuba, Don L. Gibbons, P. Andrew Futreal, Jianhua Zhang, Daniel Gomez, Jianjun Zhang
Published 2020-11-01