Designs for adding a treatment arm to an ongoing clinical trial

by Maxine Bennett, Adrian P. Mander
Published 2020-03-01

Re-formulating Gehan’s design as a flexible two-stage single-arm trial

by Michael J. Grayling, Adrian P. Mander
Published 2019-01-01

Sample size re-estimation in crossover trials: application to the AIM HY-INFORM study

by Julie Wych, Michael J. Grayling, Adrian P. Mander
Published 2019-12-01

AplusB: A Web Application for Investigating A + B Designs for Phase I Cancer Clinical Trials.

by Graham M Wheeler, Michael J Sweeting, Adrian P Mander
Published 2016-01-01

Ferrous sulfate supplementation causes significant gastrointestinal side-effects in adults: a systematic review and meta-analysis.

by Zoe Tolkien, Lynne Stecher, Adrian P Mander, Dora I A Pereira, Jonathan J Powell
Published 2015-01-01

Objectively measured physical activity and fat mass in children: a bias-adjusted meta-analysis of prospective studies.

by Desiree C Wilks, Stephen J Sharp, Ulf Ekelund, Simon G Thompson, Adrian P Mander, Rebecca M Turner, Susan A Jebb, Anna Karin Lindroos
Published 2011-02-01

How to design a dose-finding study using the continual reassessment method

by Graham M. Wheeler, Adrian P. Mander, Alun Bedding, Kristian Brock, Victoria Cornelius, Andrew P. Grieve, Thomas Jaki, Sharon B. Love, Lang’o Odondi, Christopher J. Weir, Christina Yap, Simon J. Bond
Published 2019-01-01

Adaptive designs in clinical trials: why use them, and how to run and report them

by Philip Pallmann, Alun W. Bedding, Babak Choodari-Oskooei, Munyaradzi Dimairo, Laura Flight, Lisa V. Hampson, Jane Holmes, Adrian P. Mander, Lang’o Odondi, Matthew R. Sydes, Sofía S. Villar, James M. S. Wason, Christopher J. Weir, Graham M. Wheeler, Christina Yap, Thomas Jaki
Published 2018-02-01

Development process of a consensus-driven CONSORT extension for randomised trials using an adaptive design

by Munyaradzi Dimairo, Elizabeth Coates, Philip Pallmann, Susan Todd, Steven A. Julious, Thomas Jaki, James Wason, Adrian P. Mander, Christopher J. Weir, Franz Koenig, Marc K. Walton, Katie Biggs, Jon Nicholl, Toshimitsu Hamasaki, Michael A. Proschan, John A. Scott, Yuki Ando, Daniel Hind, Douglas G. Altman
Published 2018-11-01

The adaptive designs CONSORT extension (ACE) statement: a checklist with explanation and elaboration guideline for reporting randomised trials that use an adaptive design

by Munyaradzi Dimairo, Philip Pallmann, James Wason, Susan Todd, Thomas Jaki, Steven A. Julious, Adrian P. Mander, Christopher J. Weir, Franz Koenig, Marc K. Walton, Jon P. Nicholl, Elizabeth Coates, Katie Biggs, Toshimitsu Hamasaki, Michael A. Proschan, John A. Scott, Yuki Ando, Daniel Hind, Douglas G. Altman, on behalf of the ACE Consensus Group
Published 2020-06-01

Regulatory T Cell Responses in Participants with Type 1 Diabetes after a Single Dose of Interleukin-2: A Non-Randomised, Open Label, Adaptive Dose-Finding Trial.

by John A Todd, Marina Evangelou, Antony J Cutler, Marcin L Pekalski, Neil M Walker, Helen E Stevens, Linsey Porter, Deborah J Smyth, Daniel B Rainbow, Ricardo C Ferreira, Laura Esposito, Kara M D Hunter, Kevin Loudon, Kathryn Irons, Jennie H Yang, Charles J M Bell, Helen Schuilenburg, James Heywood, Ben Challis, Sankalpa Neupane, Pamela Clarke, Gillian Coleman, Sarah Dawson, Donna Goymer, Katerina Anselmiova, Jane Kennet, Judy Brown, Sarah L Caddy, Jia Lu, Jane Greatorex, Ian Goodfellow, Chris Wallace, Tim I Tree, Mark Evans, Adrian P Mander, Simon Bond, Linda S Wicker, Frank Waldron-Lynch
Published 2016-10-01