Metformin from mother to unborn child – Are there unwarranted effects?

by Linh Nguyen, Shiao-Yng Chan, Adrian Kee Keong Teo
Published 2018-09-01

Comparable Generation of Activin-Induced Definitive Endoderm via Additive Wnt or BMP Signaling in Absence of Serum

by Adrian Kee Keong Teo, Ivan Achel Valdez, Ercument Dirice, Rohit N. Kulkarni
Published 2014-07-01

Dissecting diabetes/metabolic disease mechanisms using pluripotent stem cells and genome editing tools

by Adrian Kee Keong Teo, Manoj K. Gupta, Alessandro Doria, Rohit N. Kulkarni
Published 2015-09-01

Knowledge gaps in rodent pancreas biology: taking human pluripotent stem cell-derived pancreatic beta cells into our own hands

by Munirah Mohamad Santosa, Blaise Su Jun Low, Nicole Min Qian Pek, Adrian Kee Keong Teo
Published 2016-01-01

Protocol for the generation of pancreatic and hepatic progenitors from human pluripotent stem cells for gene regulatory assays

by Lay Shuen Tan, Resilind Su Ern Chew, Natasha Hui Jin Ng, Adrian Kee Keong Teo
Published 2021-06-01

Proinflammatory Cytokines Induce Endocrine Differentiation in Pancreatic Ductal Cells via STAT3-Dependent NGN3 Activation

by Ivan Achel Valdez, Ercument Dirice, Manoj K. Gupta, Jun Shirakawa, Adrian Kee Keong Teo, Rohit N. Kulkarni
Published 2016-04-01

Early Developmental Perturbations in a Human Stem Cell Model of MODY5/HNF1B Pancreatic Hypoplasia

by Adrian Kee Keong Teo, Hwee Hui Lau, Ivan Achel Valdez, Ercument Dirice, Erling Tjora, Helge Raeder, Rohit N. Kulkarni
Published 2016-03-01

PDX1 Binds and Represses Hepatic Genes to Ensure Robust Pancreatic Commitment in Differentiating Human Embryonic Stem Cells

by Adrian Kee Keong Teo, Norihiro Tsuneyoshi, Shawn Hoon, Ee Kim Tan, Lawrence W. Stanton, Christopher V.E. Wright, N. Ray Dunn
Published 2015-04-01

HNF4A Haploinsufficiency in MODY1 Abrogates Liver and Pancreas Differentiation from Patient-Derived Induced Pluripotent Stem Cells

by Natasha Hui Jin Ng, Joanita Binte Jasmen, Chang Siang Lim, Hwee Hui Lau, Vidhya Gomathi Krishnan, Juned Kadiwala, Rohit N. Kulkarni, Helge Ræder, Ludovic Vallier, Shawn Hoon, Adrian Kee Keong Teo
Published 2019-06-01

Decreased GLUT2 and glucose uptake contribute to insulin secretion defects in MODY3/HNF1A hiPSC-derived mutant β cells

by Blaise Su Jun Low, Chang Siang Lim, Shirley Suet Lee Ding, Yaw Sing Tan, Natasha Hui Jin Ng, Vidhya Gomathi Krishnan, Su Fen Ang, Claire Wen Ying Neo, Chandra S. Verma, Shawn Hoon, Su Chi Lim, E. Shyong Tai, Adrian Kee Keong Teo
Published 2021-05-01

The type 2 diabetes gene product STARD10 is a phosphoinositide-binding protein that controls insulin secretory granule biogenesis

by Gaelle R. Carrat, Elizabeth Haythorne, Alejandra Tomas, Leena Haataja, Andreas Müller, Peter Arvan, Alexandra Piunti, Kaiying Cheng, Mutian Huang, Timothy J. Pullen, Eleni Georgiadou, Theodoros Stylianides, Nur Shabrina Amirruddin, Victoria Salem, Walter Distaso, Andrew Cakebread, Kate J. Heesom, Philip A. Lewis, David J. Hodson, Linford J. Briant, Annie C.H. Fung, Richard B. Sessions, Fabien Alpy, Alice P.S. Kong, Peter I. Benke, Federico Torta, Adrian Kee Keong Teo, Isabelle Leclerc, Michele Solimena, Dale B. Wigley, Guy A. Rutter
Published 2020-10-01