Progressive dopaminergic alterations and mitochondrial abnormalities in LRRK2 G2019S knock-in mice

by M. Yue, K.M. Hinkle, P. Davies, E. Trushina, F.C. Fiesel, T.A. Christenson, A.S. Schroeder, L. Zhang, E. Bowles, B. Behrouz, S.J. Lincoln, J.E. Beevers, A.J. Milnerwood, A. Kurti, P.J. McLean, J.D. Fryer, W. Springer, D.W. Dickson, M.J. Farrer, H.L. Melrose
Published 2015-06-01

A Modified Monomeric Red Fluorescent Protein Reporter for Assessing CRISPR Activity

by Camilla Højland Knudsen, Camilla Højland Knudsen, Emilía S. Ásgrímsdóttir, Emilía S. Ásgrímsdóttir, Karim Rahimi, Karim Rahimi, Katherine P. Gill, Katherine P. Gill, Søs Frandsen, Søs Frandsen, Susanne Hvolbøl Buchholdt, Susanne Hvolbøl Buchholdt, Muwan Chen, Muwan Chen, Jørgen Kjems, Jørgen Kjems, Fabia Febbraro, Fabia Febbraro, Fabia Febbraro, Mark Denham, Mark Denham
Published 2018-05-01

RNA-Seq Expression Analysis of Chronic Asthmatic Mice with Bu-Shen-Yi-Qi Formula Treatment and Prediction of Regulated Gene Targets of Anti-Airway Remodeling

by Jie Cui, Zexi Lv, Fangzhou Teng, La Yi, Weifeng Tang, WenQian Wang, Wuniqiemu Tulake, Jingjing Qin, Xueyi Zhu, Ying Wei, Jingcheng Dong
Published 2021-01-01

Differentially Expressed miRNA-Gene Targets Related to Intramuscular Fat in Musculus Longissimus Dorsi of Charolais × Holstein F₂-Crossbred Bulls

by Bilal Ahmad Mir, Henry Reyer, Katrin Komolka, Siriluck Ponsuksili, Christa Kühn, Steffen Maak
Published 2020-06-01

Claudin-4 knockout by TALEN-mediated gene targeting in MDCK cells: Claudin-4 is dispensable...

by Shinsaku Tokuda, Toyohiro Hirai, Mikio Furuse
Published 2017-01-01

Oleuropein Activates Neonatal Neocortical Proteasomes, but Proteasome Gene Targeting by AAV9...

by Nagat El Demerdash, May W. Chen, Caitlin E. O’Brien, Shawn Adams, Ewa Kulikowicz, Lee J. Martin, Jennifer K. Lee
Published 2021-08-01

Molecular Features of Glioma Determined and Validated Using Combined TCGA and GTEx Data Analyses

by Zijiang Yang, Weiyi Gong, Ting Zhang, Heng Gao
Published 2021-09-01

Latest Developed Strategies to Minimize the Off-Target Effects in CRISPR-Cas-Mediated Genome Editing

by Muhammad Naeem, Saman Majeed, Mubasher Zahir Hoque, Irshad Ahmad
Published 2020-07-01

Gene Editing in Rat Embryonic Stem Cells to Produce In Vitro Models and In Vivo Reporters

by Yaoyao Chen, Sonia Spitzer, Sylvia Agathou, Ragnhildur Thora Karadottir, Austin Smith
Published 2017-10-01

Loss of HLTF function promotes intestinal carcinogenesis

by Sandhu Sumit, Wu Xiaoli, Nabi Zinnatun, Rastegar Mojgan, Kung Sam, Mai Sabine, Ding Hao
Published 2012-03-01

Striking Immune Phenotypes in Gene-Targeted Mice Are Driven by a Copy-Number Variant Originating from a Commercially Available C57BL/6 Strain

by Vinay S. Mahajan, Ezana Demissie, Hamid Mattoo, Vinay Viswanadham, Ajit Varki, Robert Morris, Shiv Pillai
Published 2016-05-01

Comparative evaluation of PCR amplification of RLEP, 16S rRNA, rpoT and Sod A gene targets...

by Ravindra P Turankar, Shradha Pandey, Mallika Lavania, Itu Singh, Astha Nigam, Joydeepa Darlong, Fam Darlong, Utpal Sengupta
Published 2015-01-01

Opposing activities of oncogenic MIR17HG and tumor suppressive MIR100HG clusters and their gene...

by Mary F. Lopez, Ping Niu, Lu Wang, Maryann Vogelsang, Meenakshi Gaur, Bryan Krastins, Yueqiang Zhao, Aibek Smagul, Aliya Nussupbekova, Aikan A. Akanov, I. King Jordan, Victoria V. Lunyak
Published 2017-04-01

TALENs Facilitate Single-step Seamless SDF Correction of F508del CFTR in Airway Epithelial Submucosal Gland Cell-derived CF-iPSCs

by Shingo Suzuki, R Geoffrey Sargent, Beate Illek, Horst Fischer, Alaleh Esmaeili-Shandiz, Michael J Yezzi, Albert Lee, Yanu Yang, Soya Kim, Peter Renz, Zhongxia Qi, Jingwei Yu, Marcus O Muench, Ashley I Beyer, Alessander O Guimarães, Lin Ye, Judy Chang, Eli J Fine, Thomas J Cradick, Gang Bao, Meghdad Rahdar, Matthew H Porteus, Tsuyoshi Shuto, Hirofumi Kai, Yuet W Kan, Dieter C Gruenert
Published 2016-01-01

Inhibition of azoxymethane-induced preneoplastic lesions in the rat colon by a stearic acid complexed high-amylose cornstarch using different cooking methods and assessing potential gene targets

by Yinsheng Zhao, Yongfeng Ai, Li Li, Jay-Lin Jane, Suzanne Hendrich, Diane F. Birt
Published 2014-01-01

A preliminary identification of Rf*-A619, a novel restorer gene for CMS-C in maize (Zea mays L.)

by Liu Yongming, Zhao Zhuofan, Lu Yanli, Li Chuan, Wang Jing, Dong Boxiao, Liang Bing, Qiu Tao, Zeng Wenbing, Cao Moju
Published 2016-11-01

DeltaNeTS+: elucidating the mechanism of drugs and diseases using gene expression and transcriptional regulatory networks

by Heeju Noh, Ziyi Hua, Panagiotis Chrysinas, Jason E. Shoemaker, Rudiyanto Gunawan
Published 2021-03-01

Paired CRISPR/Cas9 Nickases Mediate Efficient Site-Specific Integration of F9 into rDNA Locus of Mouse ESCs

by Yanchi Wang, Junya Zhao, Nannan Duan, Wei Liu, Yuxuan Zhang, Miaojin Zhou, Zhiqing Hu, Mai Feng, Xionghao Liu, Lingqian Wu, Zhuo Li, Desheng Liang
Published 2018-10-01