Pathway and network analysis of more than 2500 whole cancer genomes

by Matthew A. Reyna, David Haan, Marta Paczkowska, Lieven P. C. Verbeke, Miguel Vazquez, Abdullah Kahraman, Sergio Pulido-Tamayo, Jonathan Barenboim, Lina Wadi, Priyanka Dhingra, Raunak Shrestha, Gad Getz, Michael S. Lawrence, Jakob Skou Pedersen, Mark A. Rubin, David A. Wheeler, Søren Brunak, Jose M. G. Izarzugaza, Ekta Khurana, Kathleen Marchal, Christian von Mering, S. Cenk Sahinalp, Alfonso Valencia, PCAWG Drivers and Functional Interpretation Working Group, Jüri Reimand, Joshua M. Stuart, Benjamin J. Raphael, PCAWG Consortium
Published 2020-02-01

Assessing the nutritional needs of men with prostate cancer

by Kaitlin McLaughlin, Lindsay Hedden, Philip Pollock, Celestia Higano, Rachel A. Murphy
Published 2019-12-01

Modulation of de Novo Lipogenesis<i> </i>Improves Response to Enzalutamide Treatment in Prostate Cancer

by Mohamed Amine Lounis, Benjamin Péant, Kim Leclerc-Desaulniers, Dwaipayan Ganguli, Caroline Daneault, Matthieu Ruiz, Amina Zoubeidi, Anne-Marie Mes-Masson, Fred Saad
Published 2020-11-01

Editorial: Intelligent Systems for Genome Functional Annotations

by Shandar Ahmad, Pedro J. Ballester, Pedro J. Ballester, Pedro J. Ballester, Pedro J. Ballester, Michael Fernandez
Published 2020-08-01

c-Myc Antagonises the Transcriptional Activity of the Androgen Receptor in Prostate Cancer Affecting Key Gene Networks

by Stefan J. Barfeld, Alfonso Urbanucci, Harri M. Itkonen, Ladan Fazli, Jessica L. Hicks, Bernd Thiede, Paul S. Rennie, Srinivasan Yegnasubramanian, Angelo M. DeMarzo, Ian G. Mills
Published 2017-04-01

Androgen receptor-binding sites are highly mutated in prostate cancer

by Tunç Morova, Daniel R. McNeill, Nada Lallous, Mehmet Gönen, Kush Dalal, David M. Wilson, Attila Gürsoy, Özlem Keskin, Nathan A. Lack
Published 2020-02-01

Correction to: ReMixT: clone-specific genomic structure estimation in cancer

by Andrew W. McPherson, Andrew Roth, Gavin Ha, Cedric Chauve, Adi Steif, Camila P. E. de Souza, Peter Eirew, Alexandre Bouchard-Côté, Sam Aparicio, S. Cenk Sahinalp, Sohrab P. Shah
Published 2017-10-01

Gonadal suppression alters axillary steroid secretions in men, but does that affect olfactory social signaling?

by Syed Imran Ali Shah, Hannah C. P. Wilson, Paul D. Abel, Richard J. Wassersug, Vít Třebický, Jitka Třebická Fialová, Caroline Allen, Hans H. Adomat, Robert H. Bell, Emma S. Tomlinson Guns, S. Craig Roberts
Published 2021-07-01

A new quinoline-based chemical probe inhibits the autophagy-related cysteine protease ATG4B

by D. Bosc, L. Vezenkov, S. Bortnik, J. An, J. Xu, C. Choutka, A. M. Hannigan, S. Kovacic, S. Loo, P. G. K. Clark, G. Chen, R. N. Guay-Ross, K. Yang, W. H. Dragowska, F. Zhang, N. E. Go, A. Leung, N. S. Honson, T. A. Pfeifer, M. Gleave, M. Bally, S. J. Jones, S. M. Gorski, R. N. Young
Published 2018-08-01

Challenges and opportunities in exosome research—Perspectives from biology, engineering, and cancer therapy

by Xia Li, Alexander L. Corbett, Erfan Taatizadeh, Nishat Tasnim, Jonathan P. Little, Cathie Garnis, Mads Daugaard, Emma Guns, Mina Hoorfar, Isaac T. S. Li
Published 2019-03-01

CRISPRi screens reveal a DNA methylation-mediated 3D genome dependent causal mechanism in prostate cancer

by Musaddeque Ahmed, Fraser Soares, Ji-Han Xia, Yue Yang, Jing Li, Haiyang Guo, Peiran Su, Yijun Tian, Hyung Joo Lee, Miranda Wang, Nayeema Akhtar, Kathleen E. Houlahan, Almudena Bosch, Stanley Zhou, Parisa Mazrooei, Junjie T. Hua, Sujun Chen, Jessica Petricca, Yong Zeng, Alastair Davies, Michael Fraser, David A. Quigley, Felix Y. Feng, Paul C. Boutros, Mathieu Lupien, Amina Zoubeidi, Liang Wang, Martin J. Walsh, Ting Wang, Shancheng Ren, Gong-Hong Wei, Housheng Hansen He
Published 2021-03-01

The novel BET‐CBP/p300 dual inhibitor NEO2734 is active in SPOP mutant and wild‐type prostate cancer

by Yuqian Yan, Jian Ma, Dejie Wang, Dong Lin, Xiaodong Pang, Shangqian Wang, Yu Zhao, Lei Shi, Hui Xue, Yunqian Pan, Jun Zhang, Claes Wahlestedt, Francis J Giles, Yu Chen, Martin E Gleave, Collin C Collins, Dingwei Ye, Yuzhuo Wang, Haojie Huang
Published 2019-11-01

Androgen-regulated transcription of ESRP2 drives alternative splicing patterns in prostate cancer

by Jennifer Munkley, Ling Li, S R Gokul Krishnan, Gerald Hysenaj, Emma Scott, Caroline Dalgliesh, Htoo Zarni Oo, Teresa Mendes Maia, Kathleen Cheung, Ingrid Ehrmann, Karen E Livermore, Hanna Zielinska, Oliver Thompson, Bridget Knight, Paul McCullagh, John McGrath, Malcolm Crundwell, Lorna W Harries, Mads Daugaard, Simon Cockell, Nuno L Barbosa-Morais, Sebastian Oltean, David J Elliott
Published 2019-09-01

The molecular function of kallikrein‐related peptidase 14 demonstrates a key modulatory role in advanced prostate cancer

by Thomas Kryza, Nathalie Bock, Scott Lovell, Anja Rockstroh, Melanie L. Lehman, Adam Lesner, Janaththani Panchadsaram, Lakmali Munasinghage Silva, Srilakshmi Srinivasan, Cameron E. Snell, Elizabeth D. Williams, Ladan Fazli, Martin Gleave, Jyotsna Batra, Colleen Nelson, Edward W. Tate, Jonathan Harris, John D. Hooper, Judith A. Clements
Published 2020-01-01

Insulin Enhances Migration and Invasion in Prostate Cancer Cells by Up-Regulation of FOXC2

by Phoebe L. Sarkar, Wendy Lee, Elizabeth D. Williams, Amy A. Lubik, Nataly Stylianou, Ali Shokoohmand, Melanie L. Lehman, Melanie L. Lehman, Brett G. Hollier, Jennifer H. Gunter, Colleen C. Nelson
Published 2019-07-01

The Terry Fox Research Institute Canadian Prostate Cancer Biomarker Network: an analysis of a pan-Canadian multi-center cohort for biomarker validation

by Véronique Ouellet, Armen Aprikian, Alain Bergeron, Fadi Brimo, Robert G. Bristow, Simone Chevalier, Darrel Drachenberg, Ladan Fazli, Neil E. Fleshner, Martin Gleave, Pierre Karakiewicz, Laurence Klotz, Louis Lacombe, Jean-Baptiste Lattouf, Theodorus van der Kwast, Jeremy A. Squire, Mathieu Latour, Dominique Trudel, Anne-Marie Mes-Masson, Fred Saad
Published 2018-09-01

ReMixT: clone-specific genomic structure estimation in cancer

by Andrew W. McPherson, Andrew Roth, Gavin Ha, Cedric Chauve, Adi Steif, Camila P. E. de Souza, Peter Eirew, Alexandre Bouchard-Côté, Sam Aparicio, S. Cenk Sahinalp, Sohrab P. Shah
Published 2017-07-01

Androgen deprivation upregulates SPINK1 expression and potentiates cellular plasticity in prostate cancer

by Ritika Tiwari, Nishat Manzar, Vipul Bhatia, Anjali Yadav, Mushtaq A. Nengroo, Dipak Datta, Shannon Carskadon, Nilesh Gupta, Michael Sigouros, Francesca Khani, Matti Poutanen, Amina Zoubeidi, Himisha Beltran, Nallasivam Palanisamy, Bushra Ateeq
Published 2020-01-01

A noncanonical AR addiction drives enzalutamide resistance in prostate cancer

by Yundong He, Ting Wei, Zhenqing Ye, Jacob J. Orme, Dong Lin, Haoyue Sheng, Ladan Fazli, R. Jeffrey Karnes, Rafael Jimenez, Liguo Wang, Liewei Wang, Martin E. Gleave, Yuzhuo Wang, Lei Shi, Haojie Huang
Published 2021-03-01

Retinoblastoma protein (Rb) links hypoxia to altered mechanical properties in cancer cells as measured by an optical tweezer

by S. Khakshour, M. P. Labrecque, H. Esmaeilsabzali, F. J. S. Lee, M. E. Cox, E. J. Park, T. V. Beischlag
Published 2017-08-01