Targeting autophagy: a novel anticancer strategy with therapeutic implications for imatinib resistance

by Jennifer S Carew, Steffan T Nawrocki, Francis J Giles, John L Cleveland
Published 2008-06-01

Evolving Therapeutic Strategies for the Classic Philadelphia-Negative Myeloproliferative Neoplasms

by Jason B. Kaplan, Brady L. Stein, Brandon McMahon, Francis J. Giles, Leonidas C. Platanias
Published 2016-01-01

Heightened JNK Activation and Reduced XIAP Levels Promote TRAIL and Sunitinib-Mediated Apoptosis in Colon Cancer Models

by Devalingam Mahalingam, Jennifer S. Carew, Claudia M. Espitia, Robbert H. Cool, Francis J. Giles, Steven de Jong, Steffan T. Nawrocki
Published 2019-06-01

9-ING-41, a small molecule inhibitor of GSK-3beta, potentiates the effects of anticancer therapeutics in bladder cancer

by Hiroo Kuroki, Tsutomu Anraku, Akira Kazama, Vladimir Bilim, Masayuki Tasaki, Daniel Schmitt, Andrew P. Mazar, Francis J Giles, Andrey Ugolkov, Yoshihiko Tomita
Published 2019-12-01

ELR510444 inhibits tumor growth and angiogenesis by abrogating HIF activity and disrupting microtubules in renal cell carcinoma.

by Jennifer S Carew, Juan A Esquivel, Claudia M Espitia, Christoph M Schultes, Marcel Mülbaier, Joe D Lewis, Bernd Janssen, Francis J Giles, Steffan T Nawrocki
Published 2012-01-01

FGFR3–TACC3: A novel gene fusion in cervical cancer

by Benedito A. Carneiro, Julia A. Elvin, Suneel D. Kamath, Siraj M. Ali, Ajit S. Paintal, Alvaro Restrepo, Emily Berry, Francis J. Giles, Melissa L. Johnson
Published 2015-08-01

Preclinical Testing of Erlotinib in a Transgenic Alveolar Rhabdomyosarcoma Mouse Model

by Jinu Abraham, Laura D. Nelon, Courtney B. Kubicek, Aoife Kilcoyne, Sheila T. Hampton, Lee Ann Zarzabal, Francis J. Giles, Joel E. Michalek, Brian P. Rubin, Charles Keller
Published 2011-01-01

The novel BET‐CBP/p300 dual inhibitor NEO2734 is active in SPOP mutant and wild‐type prostate cancer

by Yuqian Yan, Jian Ma, Dejie Wang, Dong Lin, Xiaodong Pang, Shangqian Wang, Yu Zhao, Lei Shi, Hui Xue, Yunqian Pan, Jun Zhang, Claes Wahlestedt, Francis J Giles, Yu Chen, Martin E Gleave, Collin C Collins, Dingwei Ye, Yuzhuo Wang, Haojie Huang
Published 2019-11-01