Conditionally Reprogrammed Cells from Patient-Derived Xenograft to Model Neuroendocrine Prostate Cancer Development

by Xinpei Ci, Jun Hao, Xin Dong, Hui Xue, Rebecca Wu, Stephen Yiu Chuen Choi, Anne M. Haegert, Colin C. Collins, Xuefeng Liu, Dong Lin, Yuzhuo Wang
Published 2020-06-01

The Multifaceted Roles of STAT3 Signaling in the Progression of Prostate Cancer

by Jennifer L. Bishop, Daksh Thaper, Amina Zoubeidi
Published 2014-04-01

Mutation of an L-Type Calcium Channel Gene Leads to T Lymphocyte Dysfunction

by Franz Fenninger, Franz Fenninger, Franz Fenninger, Franz Fenninger, Franz Fenninger, Jeffrey Han, Shawna R. Stanwood, Shawna R. Stanwood, Shawna R. Stanwood, Shawna R. Stanwood, Shawna R. Stanwood, Lilian L. Nohara, Lilian L. Nohara, Lilian L. Nohara, Hitesh Arora, Hitesh Arora, Hitesh Arora, Hitesh Arora, Hitesh Arora, Kyung Bok Choi, Kyung Bok Choi, Kyung Bok Choi, Kyung Bok Choi, Lonna Munro, Lonna Munro, Lonna Munro, Lonna Munro, Cheryl G. Pfeifer, Cheryl G. Pfeifer, Cheryl G. Pfeifer, Cheryl G. Pfeifer, Iryna Shanina, Marc S. Horwitz, Wilfred A. Jefferies, Wilfred A. Jefferies, Wilfred A. Jefferies, Wilfred A. Jefferies, Wilfred A. Jefferies, Wilfred A. Jefferies, Wilfred A. Jefferies
Published 2019-10-01

Development of a bispecific immune engager using a recombinant malaria protein

by Mie A. Nordmaj, Morgan E. Roberts, Emilie S. Sachse, Robert Dagil, Anne Poder Andersen, Nanna Skeltved, Kaare V. Grunddal, Sayit Mahmut Erdoğan, Swati Choudhary, Tobias Gustsavsson, Maj Sofie Ørum-Madsen, Igor Moskalev, Weihua Tian, Zhang Yang, Thomas M. Clausen, Thor G. Theander, Mads Daugaard, Morten A. Nielsen, Ali Salanti
Published 2021-04-01

The Androgen Receptor Bridges Stem Cell-Associated Signaling Nodes in Prostate Stem Cells

by Alastair H. Davies, Amina Zoubeidi
Published 2016-01-01

HASLR: Fast Hybrid Assembly of Long Reads

by Ehsan Haghshenas, Hossein Asghari, Jens Stoye, Cedric Chauve, Faraz Hach
Published 2020-08-01

Therapeutic Inhibition of Myc in Cancer. Structural Bases and Computer-Aided Drug Discovery Approaches

by Lavinia A. Carabet, Paul S. Rennie, Artem Cherkasov
Published 2018-12-01

Inhibition of Scavenger Receptor Class B Type 1 (SR-B1) Expression and Activity as a Potential Novel Target to Disrupt Cholesterol Availability in Castration-Resistant Prostate Can...

by Mitali Pandey, Grace Cuddihy, Jacob A. Gordon, Michael E. Cox, Kishor M. Wasan
Published 2021-09-01

Computer-Aided Discovery of Small Molecule Inhibitors of Thymocyte Selection-Associated High Mobility Group Box Protein (TOX) as Potential Therapeutics for Cutaneous T-Cell Lymphom...

by Vibudh Agrawal, Mingwan Su, Yuanshen Huang, Michael Hsing, Artem Cherkasov, Youwen Zhou
Published 2019-09-01

3D Printing Breast Tissue Models: A Review of Past Work and Directions for Future Work

by Chantell Cleversey, Meghan Robinson, Stephanie M. Willerth
Published 2019-07-01

Co‐targeting driver pathways in prostate cancer: two birds with one stone

by Amina Zoubeidi, Martin E Gleave
Published 2018-04-01

Abi1 loss drives prostate tumorigenesis through activation of EMT and non-canonical WNT signaling

by Disharee Nath, Xiang Li, Claudia Mondragon, Dawn Post, Ming Chen, Julie R. White, Anita Hryniewicz-Jankowska, Tiffany Caza, Vladimir A. Kuznetsov, Heidi Hehnly, Tamara Jamaspishvili, David M. Berman, Fan Zhang, Sonia H. Y. Kung, Ladan Fazli, Martin E. Gleave, Gennady Bratslavsky, Pier Paolo Pandolfi, Leszek Kotula
Published 2019-09-01

IRE1α-XBP1s pathway promotes prostate cancer by activating c-MYC signaling

by Xia Sheng, Hatice Zeynep Nenseth, Su Qu, Omer F. Kuzu, Turid Frahnow, Lukas Simon, Stephanie Greene, Qingping Zeng, Ladan Fazli, Paul S. Rennie, Ian G. Mills, Håvard Danielsen, Fabian Theis, John B. Patterson, Yang Jin, Fahri Saatcioglu
Published 2019-01-01

A novel mechanism of SRRM4 in promoting neuroendocrine prostate cancer development via a pluripotency gene networkResearch in context

by Ahn R. Lee, Yu Gan, Yuxin Tang, Xuesen Dong
Published 2018-09-01

Markers of MEK inhibitor resistance in low-grade serous ovarian cancer: EGFR is a potential therapeutic target

by Marta Llaurado Fernandez, Amy Dawson, Joshua Hoenisch, Hannah Kim, Sylvia Bamford, Clara Salamanca, Gabriel DiMattia, Trevor Shepherd, Mattia Cremona, Bryan Hennessy, Shawn Anderson, Stanislav Volik, Colin C. Collins, David G. Huntsman, Mark S. Carey
Published 2019-01-01

Deep Learning Modeling of Androgen Receptor Responses to Prostate Cancer Therapies

by Oliver Snow, Nada Lallous, Martin Ester, Artem Cherkasov
Published 2020-08-01

miR-100-5p inhibition induces apoptosis in dormant prostate cancer cells and prevents the emergence of castration-resistant prostate cancer

by Noushin Nabavi, Nur Ridzwan Nur Saidy, Erik Venalainen, Anne Haegert, Abhijit Parolia, Hui Xue, Yuwei Wang, Rebecca Wu, Xin Dong, Colin Collins, Francesco Crea, Yuzhuo Wang
Published 2017-06-01

East Indian Sandalwood Oil Is a Phosphodiesterase Inhibitor: A New Therapeutic Option in the Treatment of Inflammatory Skin Disease

by Manju Sharma, Corey Levenson, John C. Browning, Emily M. Becker, Ian Clements, Paul Castella, Michael E. Cox, Michael E. Cox
Published 2018-03-01

Distinct DNA methylation patterns associated with treatment resistance in metastatic castration resistant prostate cancer

by Madonna R. Peter, Misha Bilenky, Alastair Davies, Ruth Isserlin, Gary D. Bader, Neil E. Fleshner, Martin Hirst, Amina Zoubeidi, Bharati Bapat
Published 2021-03-01

Reversing pathology in a preclinical model of Alzheimer's disease by hacking cerebrovascular neoangiogenesis with advanced cancer therapeutics

by Chaahat S.B. Singh, Kyung Bok Choi, Lonna Munro, Hong Yue Wang, Cheryl G. Pfeifer, Wilfred A. Jefferies
Published 2021-09-01