The PTEN–PI3K Axis in Cancer

by Antonella Papa, Pier Paolo Pandolfi
Published 2019-04-01

The Interplay Between the Genetic and Immune Landscapes of AML: Mechanisms and Implications for Risk Stratification and Therapy

by Lourdes M. Mendez, Lourdes M. Mendez, Ryan R. Posey, Ryan R. Posey, Pier Paolo Pandolfi, Pier Paolo Pandolfi
Published 2019-11-01

The Mouse Hospital and Its Integration in Ultra-Precision Approaches to Cancer Care

by John G. Clohessy, John G. Clohessy, Pier Paolo Pandolfi
Published 2018-08-01

Functional connection between Rad51 and PML in homology-directed repair.

by Sergei Boichuk, Liang Hu, Kathleen Makielski, Pier Paolo Pandolfi, Ole V Gjoerup
Published 2011-01-01

PTENP1 is a ceRNA for PTEN: it’s CRISPR clear

by Marianna Vitiello, Monica Evangelista, Yang Zhang, Leonardo Salmena, Pier Paolo Pandolfi, Laura Poliseno
Published 2020-06-01

Characterization of Dual PTEN and p53-Targeting MicroRNAs Identifies MicroRNA-638/Dnm2 as a Two-Hit Oncogenic Locus

by Yvonne Tay, Shen Mynn Tan, Florian A. Karreth, Judy Lieberman, Pier Paolo Pandolfi
Published 2014-08-01

Bone Marrow Endosteal Mesenchymal Progenitors Depend on HIF Factors for Maintenance and Regulation of Hematopoiesis

by Jlenia Guarnerio, Nadia Coltella, Ugo Ala, Giovanni Tonon, Pier Paolo Pandolfi, Rosa Bernardi
Published 2014-06-01

Identification of competing endogenous RNAs of the tumor suppressor gene PTEN: A probabilistic approach

by Kourosh Zarringhalam, Yvonne Tay, Prajna Kulkarni, Assaf C. Bester, Pier Paolo Pandolfi, Rahul V. Kulkarni
Published 2017-08-01

mTOR Promotes Survival and Astrocytic Characteristics Induced by Pten/Akt Signaling in Glioblastoma

by Xiaoyi Hu, Pier Paolo Pandolfi, Yi Li, Jason A. Koutcher, Marc Rosenblum, Eric C. Holland
Published 2005-04-01

Optimized RNA-targeting CRISPR/Cas13d technology outperforms shRNA in identifying functional circRNAs

by Yang Zhang, Tuan M. Nguyen, Xiao-Ou Zhang, Limei Wang, Tin Phan, John G. Clohessy, Pier Paolo Pandolfi
Published 2021-01-01

A non-cell-autonomous role for Pml in the maintenance of leukemia from the niche

by Jlenia Guarnerio, Lourdes Maria Mendez, Noboru Asada, Archita Venugopal Menon, Jacqueline Fung, Kelsey Berry, Paul S. Frenette, Keisuke Ito, Pier Paolo Pandolfi
Published 2018-01-01

Promyelocytic leukemia zinc finger protein activates GATA4 transcription and mediates cardiac hypertrophic signaling from angiotensin II receptor 2.

by Ning Wang, Gerald D Frank, Ronghua Ding, Zhongjia Tan, Amita Rachakonda, Pier Paolo Pandolfi, Takaaki Senbonmatsu, Erwin J Landon, Tadashi Inagami
Published 2012-01-01

Amplification of the angiogenic signal through the activation of the TSC/mTOR/HIF axis by the KSHV vGPCR in Kaposi's sarcoma.

by Bruno C Jham, Tao Ma, Jiadi Hu, Risa Chaisuparat, Eitan R Friedman, Pier Paolo Pandolfi, Abraham Schneider, Akrit Sodhi, Silvia Montaner
Published 2011-04-01

The proto-oncogene LRF is under post-transcriptional control of MiR-20a: implications for senescence.

by Laura Poliseno, Letizia Pitto, Marcella Simili, Laura Mariani, Luisa Riccardi, Alessia Ciucci, Milena Rizzo, Monica Evangelista, Alberto Mercatanti, Pier Paolo Pandolfi, Giuseppe Rainaldi
Published 2008-07-01

CIP2A promotes proliferation of spermatogonial progenitor cells and spermatogenesis in mice.

by Sami Ventelä, Christophe Côme, Juho-Antti Mäkelä, Robin M Hobbs, Leni Mannermaa, Markku Kallajoki, Edward K Chan, Pier Paolo Pandolfi, Jorma Toppari, Jukka Westermarck
Published 2012-01-01

The RNA binding protein ESRP1 fine-tunes the expression of pluripotency-related factors in mouse embryonic stem cells.

by Sharmila Fagoonee, Claudia Bearzi, Ferdinando Di Cunto, John G Clohessy, Roberto Rizzi, Markus Reschke, Emanuela Tolosano, Paolo Provero, Pier Paolo Pandolfi, Lorenzo Silengo, Fiorella Altruda
Published 2013-01-01

Deregulated PP1α phosphatase activity towards MAPK activation is antagonized by a tumor suppressive failsafe mechanism

by Ming Chen, Lixin Wan, Jiangwen Zhang, Jinfang Zhang, Lourdes Mendez, John G. Clohessy, Kelsey Berry, Joshua Victor, Qing Yin, Yuan Zhu, Wenyi Wei, Pier Paolo Pandolfi
Published 2018-01-01

Characterization and Analysis of the Composition and Dynamics of the Mammalian Riboproteome

by Markus Reschke, John G. Clohessy, Nina Seitzer, Daniel P. Goldstein, Susanne B. Breitkopf, Daniel B. Schmolze, Ugo Ala, John M. Asara, Andrew H. Beck, Pier Paolo Pandolfi
Published 2013-09-01

Copper Promotes Tumorigenesis by Activating the PDK1‐AKT Oncogenic Pathway in a Copper Transporter 1 Dependent Manner

by Jianping Guo, Ji Cheng, Nana Zheng, Xiaomei Zhang, Xiaoming Dai, Linli Zhang, Changjiang Hu, Xueji Wu, Qiwei Jiang, Depei Wu, Hitoshi Okada, Pier Paolo Pandolfi, Wenyi Wei
Published 2021-09-01

Interplay between c-Src and the APC/C co-activator Cdh1 regulates mammary tumorigenesis

by Tao Han, Shulong Jiang, Hong Zheng, Qing Yin, Mengyu Xie, Margaret R Little, Xiu Yin, Ming Chen, Su Jung Song, Amer A. Beg, Pier Paolo Pandolfi, Lixin Wan
Published 2019-08-01