Mechanisms of functional compensation, delineated by eigenvector centrality mapping, across the pathophysiological continuum of Alzheimer’s disease

by Stavros Skouras, Carles Falcon, Alan Tucholka, Lorena Rami, Raquel Sanchez-Valle, Albert Lladó, Juan D. Gispert, José Luís Molinuevo
Published 2019-01-01

CSF glial biomarkers YKL40 and sTREM2 are associated with longitudinal volume and diffusivity changes in cognitively unimpaired individuals

by Carles Falcon, Gemma C. Monté-Rubio, Oriol Grau-Rivera, Marc Suárez-Calvet, Raquel Sánchez-Valle, Lorena Rami, Beatriz Bosch, Christian Haass, Juan Domingo Gispert, José Luis Molinuevo
Published 2019-01-01

Projection to Latent Spaces Disentangles Pathological Effects on Brain Morphology in the Asymptomatic Phase of Alzheimer's Disease

by Adrià Casamitjana, Paula Petrone, José Luis Molinuevo, José Luis Molinuevo, José Luis Molinuevo, Juan Domingo Gispert, Juan Domingo Gispert, Juan Domingo Gispert, Verónica Vilaplana
Published 2020-07-01

Strategies to reduce sample sizes in Alzheimer’s disease primary and secondary prevention trials using longitudinal amyloid PET imaging

by Isadora Lopes Alves, Fiona Heeman, Lyduine E. Collij, Gemma Salvadó, Nelleke Tolboom, Natàlia Vilor-Tejedor, Pawel Markiewicz, Maqsood Yaqub, David Cash, Elizabeth C. Mormino, Philip S. Insel, Ronald Boellaard, Bart N. M. van Berckel, Adriaan A. Lammertsma, Frederik Barkhof, Juan Domingo Gispert
Published 2021-04-01

Theoretical frameworks and approaches used within the Reserve, Resilience and Protective Factors professional interest area of the Alzheimer's Association International Society to...

by David Bartrés‐Faz, Eider Arenaza‐Urquijo, Michael Ewers, Sylvie Belleville, Gaël Chételat, Nicolai Franzmeier, Julie Gonneaud, José María González deEchevarri, Ozioma Okonkwo, Stephanie Schultz, Michael Valenzuela, Yaakov Stern, Prashanthi Vemuri
Published 2020-01-01

Leptin alters energy intake and fat mass but not energy expenditure in lean subjects

by Pavlina Chrysafi, Nikolaos Perakakis, Olivia M. Farr, Konstantinos Stefanakis, Natia Peradze, Aleix Sala-Vila, Christos S. Mantzoros
Published 2020-10-01

Secondary prevention of Alzheimer’s dementia: neuroimaging contributions

by Mara ten Kate, Silvia Ingala, Adam J. Schwarz, Nick C. Fox, Gaël Chételat, Bart N. M. van Berckel, Michael Ewers, Christopher Foley, Juan Domingo Gispert, Derek Hill, Michael C. Irizarry, Adriaan A. Lammertsma, José Luis Molinuevo, Craig Ritchie, Philip Scheltens, Mark E. Schmidt, Pieter Jelle Visser, Adam Waldman, Joanna Wardlaw, Sven Haller, Frederik Barkhof
Published 2018-10-01

The influence of diversity on the measurement of functional impairment: An international validation of the Amsterdam IADL Questionnaire in eight countries

by Mark A. Dubbelman, Merike Verrijp, David Facal, Gonzalo Sánchez‐Benavides, Laura J.E. Brown, Wiesje M. vander Flier, Hanna Jokinen, Athene Lee, Iracema Leroi, Cristina Lojo‐Seoane, Vuk Milošević, José Luís Molinuevo, Arturo X. Pereiro Rozas, Craig Ritchie, Stephen Salloway, Gemma Stringer, Stelios Zygouris, Bruno Dubois, Stéphane Epelbaum, Philip Scheltens, Sietske A.M. Sikkes
Published 2020-01-01

Improving the resistance and resilience framework for aging and dementia studies

by Eider M. Arenaza-Urquijo, Prashanthi Vemuri
Published 2020-04-01

Awareness of Cognitive Decline in Patients With Alzheimer's Disease: A Systematic Review and Meta-Analysis

by Federica Cacciamani, Federica Cacciamani, Federica Cacciamani, Federica Cacciamani, Federica Cacciamani, Marion Houot, Marion Houot, Marion Houot, Geoffroy Gagliardi, Geoffroy Gagliardi, Bruno Dubois, Bruno Dubois, Bruno Dubois, Bruno Dubois, Bruno Dubois, Sietske Sikkes, Sietske Sikkes, Gonzalo Sánchez-Benavides, Gonzalo Sánchez-Benavides, Gonzalo Sánchez-Benavides, Elena Denicolò, José Luis Molinuevo, Patrizia Vannini, Patrizia Vannini, Stéphane Epelbaum, Stéphane Epelbaum, Stéphane Epelbaum, Stéphane Epelbaum, Stéphane Epelbaum, Stéphane Epelbaum
Published 2021-08-01

Plasma levels of soluble TREM2 and neurofilament light chain in TREM2 rare variant carriers

by Nicholas J. Ashton, Marc Suárez-Calvet, Amanda Heslegrave, Abdul Hye, Cristina Razquin, Pau Pastor, Raquel Sanchez-Valle, José L. Molinuevo, Pieter Jelle Visser, Kaj Blennow, Angela K. Hodges, Henrik Zetterberg
Published 2019-11-01

FLAME: A computerized neuropsychological composite for trials in early dementia

by Helen Brooker, Gareth Williams, Adam Hampshire, Anne Corbett, Dag Aarsland, Jeffrey Cummings, Jose Luis Molinuevo, Alireza Atri, Zahinoor Ismail, Byron Creese, Tormod Fladby, Charlotte Thim‐Hansen, Keith Wesnes, Clive Ballard
Published 2020-01-01

Higher CSF sTREM2 and microglia activation are associated with slower rates of beta‐amyloid accumulation

by Michael Ewers, Gloria Biechele, Marc Suárez‐Calvet, Christian Sacher, Tanja Blume, Estrella Morenas‐Rodriguez, Yuetiva Deming, Laura Piccio, Carlos Cruchaga, Gernot Kleinberger, Leslie Shaw, John Q Trojanowski, Jochen Herms, Martin Dichgans, the Alzheimer's Disease Neuroimaging Initiative (ADNI), Matthias Brendel, Christian Haass, Nicolai Franzmeier
Published 2020-09-01

Use of mild cognitive impairment and prodromal AD/MCI due to AD in clinical care: a European survey

by Daniela Bertens, Stephanie Vos, Patrick Kehoe, Henrike Wolf, Flavio Nobili, Alexandre Mendonça, Ineke van Rossum, Jacub Hort, Jose Luis Molinuevo, Michael Heneka, Ron Petersen, Philip Scheltens, Pieter Jelle Visser
Published 2019-08-01

Mild developmental foreign accent syndrome and psychiatric comorbidity: Altered white matter integrity in speech and emotion regulation networks

by Marcelo L Berthier, Núria Roé-Vellvé, Ignacio Moreno-Torres, Carles Falcon, Karl Thurnhofer-Hemsi, Karl Thurnhofer-Hemsi, José Paredes-Pacheco, José Paredes-Pacheco, María José Torres-Prioris, María José Torres-Prioris, Irene De Torres, Irene De Torres, Francisco Alfaro, Antonio Luis Gutierrez Cardo, Miquel Baquero, Rafael Ruiz-Cruces, Guadalupe Dávila, Guadalupe Dávila
Published 2016-08-01

Optimized dual-time-window protocols for quantitative [18F]flutemetamol and [18F]florbetaben PET studies

by Fiona Heeman, Maqsood Yaqub, Isadora Lopes Alves, Kerstin Heurling, Johannes Berkhof, Juan Domingo Gispert, Santiago Bullich, Christopher Foley, Adriaan A. Lammertsma, on behalf of the AMYPAD Consortium
Published 2019-03-01

Combined 18F-FDG-PET and diffusion tensor imaging in mesial temporal lobe epilepsy with hippocampal sclerosis

by Javier Aparicio, Mar Carreño, Núria Bargalló, Xavier Setoain, Sebastià Rubí, Jordi Rumià, Carles Falcón, Anna Calvo, Berta Martí-Fuster, Nelly Padilla, Teresa Boget, Luís Pintor, Antonio Donaire
Published 2016-01-01

Association between polygenic risk score of Alzheimer’s disease and plasma phosphorylated tau in individuals from the Alzheimer’s Disease Neuroimaging Initiative

by Anna Zettergren, Jodie Lord, Nicholas J. Ashton, Andrea L. Benedet, Thomas K. Karikari, Juan Lantero Rodriguez, the Alzheimer’s Disease Neuroimaging Initiative*, Anniina Snellman, Marc Suárez-Calvet, Petroula Proitsi, Henrik Zetterberg, Kaj Blennow
Published 2021-01-01

Higher CSF sTREM2 attenuates ApoE4-related risk for cognitive decline and neurodegeneration

by Nicolai Franzmeier, M. Suárez-Calvet, Lukas Frontzkowski, Annah Moore, Timothy J. Hohman, Estrella Morenas-Rodriguez, Brigitte Nuscher, Leslie Shaw, John Q. Trojanowski, Martin Dichgans, Gernot Kleinberger, Christian Haass, Michael Ewers, for the Alzheimer’s Disease Neuroimaging Initiative (ADNI)
Published 2020-10-01

Aging-Dependent Genetic Effects Associated to ADHD Predict Longitudinal Changes of Ventricular Volumes in Adulthood

by Natalia Vilor-Tejedor, Natalia Vilor-Tejedor, Natalia Vilor-Tejedor, Natalia Vilor-Tejedor, Mohammad Arfan Ikram, Mohammad Arfan Ikram, Mohammad Arfan Ikram, Gennady Roshchupkin, Gennady Roshchupkin, Elisabeth J. Vinke, Elisabeth J. Vinke, Meike W. Vernooij, Meike W. Vernooij, Hieab H. H. Adams, Hieab H. H. Adams, Hieab H. H. Adams
Published 2020-06-01