Time to Amyloid Positivity and Preclinical Changes in Brain Metabolism, Atrophy, and Cognition: Evidence for Emerging Amyloid Pathology in Alzheimer's Disease

by Philip S. Insel, Philip S. Insel, Philip S. Insel, Rik Ossenkoppele, Devon Gessert, William Jagust, William Jagust, Susan Landau, Susan Landau, Oskar Hansson, Oskar Hansson, Michael W. Weiner, Michael W. Weiner, Niklas Mattsson, Niklas Mattsson, Niklas Mattsson, for the Alzheimer's Disease Neuroimaging Initiative
Published 2017-05-01

Time between milestone events in the Alzheimer's disease amyloid cascade

by Philip S. Insel, Michael C. Donohue, David Berron, Oskar Hansson, Niklas Mattsson-Carlgren
Published 2021-02-01

The A4 study: β‐amyloid and cognition in 4432 cognitively unimpaired adults

by Philip S. Insel, Michael C. Donohue, Reisa Sperling, Oskar Hansson, Niklas Mattsson‐Carlgren
Published 2020-05-01

Differences in prefrontal, limbic, and white matter lesion volumes according to cognitive status in elderly patients with first-onset subsyndromal depression.

by Jun-Young Lee, Soowon Park, Scott Mackin, Michael Ewers, Helena Chui, William Jagust, Philip S Insel, Michael W Weiner
Published 2014-01-01

Increased amyloidogenic APP processing in APOE ɛ4-negative individuals with cerebral β-amyloidosis

by Niklas Mattsson, Philip S. Insel, Sebastian Palmqvist, Erik Stomrud, Danielle van Westen, Lennart Minthon, Henrik Zetterberg, Kaj Blennow, Oskar Hansson
Published 2016-03-01

Study partner‐reported decline identifies cognitive decline and dementia risk

by Rachel L. Nosheny, Chengshi Jin, John Neuhaus, Philip S. Insel, Robert Scott Mackin, Michael W. Weiner, Alzheimer’s Disease Neuroimaging Initiative investigators
Published 2019-12-01

Assessing risk for preclinical β‐amyloid pathology with APOE, cognitive, and demographic information

by Philip S. Insel, Sebastian Palmqvist, R. Scott Mackin, Rachel L. Nosheny, Oskar Hansson, Michael W. Weiner, Niklas Mattsson, Alzheimer's Disease Neuroimaging Initiative
Published 2016-01-01

Comparing progression biomarkers in clinical trials of early Alzheimer’s disease

by Nicholas C. Cullen, Henrik Zetterberg, Philip S. Insel, Bob Olsson, Ulf Andreasson, the Alzheimer’s Disease Neuroimaging Initiative, Kaj Blennow, Oskar Hansson, Niklas Mattsson‐Carlgren
Published 2020-09-01

Cerebrospinal fluid and plasma biomarker trajectories with increasing amyloid deposition in Alzheimer's disease

by Sebastian Palmqvist, Philip S Insel, Erik Stomrud, Shorena Janelidze, Henrik Zetterberg, Britta Brix, Udo Eichenlaub, Jeffrey L Dage, Xiyun Chai, Kaj Blennow, Niklas Mattsson, Oskar Hansson
Published 2019-12-01

Unsupervised online neuropsychological test performance for individuals with mild cognitive impairment and dementia: Results from the Brain Health Registry

by R. Scott Mackin, Philip S. Insel, Diana Truran, Shannon Finley, Derek Flenniken, Rachel Nosheny, Aaron Ulbright, Monica Comacho, David Bickford, Brian Harel, Paul Maruff, Michael W. Weiner
Published 2018-01-01

Mild behavioral impairment and its relation to tau pathology in preclinical Alzheimer’s disease

by Maurits Johansson, Erik Stomrud, Philip S. Insel, Antoine Leuzy, Per Mårten Johansson, Ruben Smith, Zahinoor Ismail, Shorena Janelidze, Sebastian Palmqvist, Danielle van Westen, Niklas Mattsson-Carlgren, Oskar Hansson
Published 2021-01-01

Preclinical effects of APOE ε4 on cerebrospinal fluid Aβ42 concentrations

by Ronald Lautner, Philip S. Insel, Tobias Skillbäck, Bob Olsson, Mikael Landén, Giovanni B. Frisoni, Sanna-Kaisa Herukka, Harald Hampel, Anders Wallin, Lennart Minthon, Oskar Hansson, Kaj Blennow, Niklas Mattsson, Henrik Zetterberg
Published 2017-10-01

Strategies to reduce sample sizes in Alzheimer’s disease primary and secondary prevention trials using longitudinal amyloid PET imaging

by Isadora Lopes Alves, Fiona Heeman, Lyduine E. Collij, Gemma Salvadó, Nelleke Tolboom, Natàlia Vilor-Tejedor, Pawel Markiewicz, Maqsood Yaqub, David Cash, Elizabeth C. Mormino, Philip S. Insel, Ronald Boellaard, Bart N. M. van Berckel, Adriaan A. Lammertsma, Frederik Barkhof, Juan Domingo Gispert
Published 2021-04-01