BACE1 Inhibitor MK-8931 Alters Formation but Not Stability of Dendritic Spines

by Tanja Blume, Severin Filser, Anna Jaworska, Jean-Francois Blain, Gerhard Koenig, Katrin Moschke, Katrin Moschke, Stefan F. Lichtenthaler, Stefan F. Lichtenthaler, Stefan F. Lichtenthaler, Jochen Herms, Jochen Herms, Jochen Herms
Published 2018-07-01

Microglial response to increasing amyloid load saturates with aging: a longitudinal dual tracer in vivo μPET-study

by Tanja Blume, Carola Focke, Finn Peters, Maximilian Deussing, Nathalie L. Albert, Simon Lindner, Franz-Josef Gildehaus, Barbara von Ungern-Sternberg, Laurence Ozmen, Karlheinz Baumann, Peter Bartenstein, Axel Rominger, Jochen Herms, Matthias Brendel
Published 2018-11-01

Data on specificity of [18F]GE180 uptake for TSPO expression in rodent brain and myocardium

by Maximilian Deussing, Tanja Blume, Lena Vomacka, Christoph Mahler, Carola Focke, Andrei Todica, Marcus Unterrainer, Nathalie L. Albert, Simon Lindner, Barbara von Ungern-Sternberg, Karlheinz Baumann, Andreas Zwergal, Peter Bartenstein, Jochen Herms, Axel Rominger, Matthias Brendel
Published 2018-08-01

Microglial activation in the right amygdala-entorhinal-hippocampal complex is associated with preserved spatial learning in AppNL-G-F mice

by Gloria Biechele, Karin Wind, Tanja Blume, Christian Sacher, Leonie Beyer, Florian Eckenweber, Nicolai Franzmeier, Michael Ewers, Benedikt Zott, Simon Lindner, Franz-Josef Gildehaus, Barbara von Ungern-Sternberg, Sabina Tahirovic, Michael Willem, Peter Bartenstein, Paul Cumming, Axel Rominger, Jochen Herms, Matthias Brendel
Published 2021-04-01

Higher CSF sTREM2 and microglia activation are associated with slower rates of beta‐amyloid accumulation

by Michael Ewers, Gloria Biechele, Marc Suárez‐Calvet, Christian Sacher, Tanja Blume, Estrella Morenas‐Rodriguez, Yuetiva Deming, Laura Piccio, Carlos Cruchaga, Gernot Kleinberger, Leslie Shaw, John Q Trojanowski, Jochen Herms, Martin Dichgans, the Alzheimer's Disease Neuroimaging Initiative (ADNI), Matthias Brendel, Christian Haass, Nicolai Franzmeier
Published 2020-09-01

Glial activation is moderated by sex in response to amyloidosis but not to tau pathology in mouse models of neurodegenerative diseases

by Gloria Biechele, Nicolai Franzmeier, Tanja Blume, Michael Ewers, Jose Medina Luque, Florian Eckenweber, Christian Sacher, Leonie Beyer, Francois Ruch-Rubinstein, Simon Lindner, Franz-Josef Gildehaus, Barbara von Ungern-Sternberg, Paul Cumming, Peter Bartenstein, Axel Rominger, Günter U. Höglinger, Jochen Herms, Matthias Brendel
Published 2020-12-01

Late-stage Anle138b treatment ameliorates tau pathology and metabolic decline in a mouse model of human Alzheimer’s disease tau

by Matthias Brendel, Maximilian Deussing, Tanja Blume, Lena Kaiser, Federico Probst, Felix Overhoff, Finn Peters, Barbara von Ungern-Sternberg, Sergey Ryazanov, Andrei Leonov, Christian Griesinger, Andreas Zwergal, Johannes Levin, Peter Bartenstein, Igor Yakushev, Paul Cumming, Guido Boening, Sibylle Ziegler, Jochen Herms, Armin Giese, Axel Rominger
Published 2019-08-01

Longitudinal TSPO expression in tau transgenic P301S mice predicts increased tau accumulation and deteriorated spatial learning

by Florian Eckenweber, Jose Medina-Luque, Tanja Blume, Christian Sacher, Gloria Biechele, Karin Wind, Maximilian Deussing, Nils Briel, Simon Lindner, Guido Boening, Barbara von Ungern-Sternberg, Marcus Unterrainer, Nathalie L. Albert, Andreas Zwergal, Johannes Levin, Peter Bartenstein, Paul Cumming, Axel Rominger, Günter U. Höglinger, Jochen Herms, Matthias Brendel
Published 2020-07-01

Comparison of 18F-T807 and 18F-THK5117 PET in a Mouse Model of Tau Pathology

by Matthias Brendel, Behrooz H. Yousefi, Behrooz H. Yousefi, Tanja Blume, Michael Herz, Carola Focke, Maximilian Deussing, Finn Peters, Simon Lindner, Barbara von Ungern-Sternberg, Alexander Drzezga, Peter Bartenstein, Peter Bartenstein, Christian Haass, Christian Haass, Christian Haass, Nobuyuki Okamura, Jochen Herms, Jochen Herms, Igor Yakushev, Igor Yakushev, Axel Rominger, Axel Rominger
Published 2018-06-01