Article 7 enzyme stability chemistry 6 nonhuman 5 controlled study 4 enzyme active site 4 enzyme activity 4 metabolism 4 unclassified drug 4 Catalytic Domain 3 Enzyme Stability 3 enzyme purification 3 hydrogen bond 3 structure analysis 3 thermostability 3 Biocatalysis 2 Enzyme Activation 2 Hydrolysis 2 Kinetics 2 Lipase 2 Models, Molecular 2 Recombinant Proteins 2 Substrate Specificity 2 amino acid sequence 2 biocatalysis 2 biocatalyst 2 catalysis 2 enzyme activation 2 enzyme mechanism 2 enzyme specificity 2