Structural basis of ligand binding to UDP-galactopyranose mutase from mycobacterium tuberculosis using substrate and tetrafluorinated substrate analogs

Structural basis of ligand binding to UDP-galactopyranose mutase from mycobacterium tuberculosis using substrate and tetrafluorinated substrate analogs

UDP-Galactopyranose mutase (UGM) is a flavin-containing enzyme that catalyses the reversible conversion of UDP-Galactopyranose (UDP-Galp) to UDP-Galactofuranose (UDP-Galf) and plays a key role in the biosynthesis of the mycobacterial cell wall galactofuran. A soluble, active form of UGM from Mycobac...

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Main Authors: van Straaten, Karin E. (Author), A. Kuttiyatveetil, Jijin R. (Author), Sevrain, Charlotte M. (Author), Villaume, Sydney A. (Author), Jimenez-Barbero, Jesus (Author), Linclau, Bruno (Author), Vincent, Stéphane P. (Author), Sanders, David A.R (Author)
Format: Article
Language:English
Published: 2015-01-15.
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