The synthesis of gemcitabine
Gemcitabine is a fluorinated nucleoside currently administered against a number of cancers. It consists of a cytosine base and a 2-deoxy-2,2-difluororibose sugar. The synthetic challenges associated with the introduction of the fluorine atoms, as well as with nucleobase introduction of 2,2-difluorin...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
2014-03-31.
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| Subjects: | |
| Online Access: | Get fulltext |