Mitigation of H 2O 2 -induced mitochondrial-mediated apoptosis in NG108-15 cells by novel mesuagenin C from Mesua kunstleri (King) kosterm

Mitigation of H 2O 2 -induced mitochondrial-mediated apoptosis in NG108-15 cells by novel mesuagenin C from Mesua kunstleri (King) kosterm

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This study was aimed to isolate and evaluate neuroprotective compounds from the hexane extract of the bark of Mesua kunstleri (Clusiaceae) on H 2O 2-induced apoptosis in NG108-15 cells. Five 4-phenylcoumarins were isolated by using various chromatographic techniques via neuroprotective activity-guid...

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Bibliographic Details
Main Authors: Abdul Kadir, H. (Author), Abdul Latif, F. (Author), Awang, K. (Author), Chan, G. (Author), Hasan, A. (Author), Ismail, N.H (Author), Kamarudin, M.N.A (Author), Wong, D.Z.H (Author)
Format: Article
Language:English
Subjects:
5,7 dihydroxy 8 (2 methylbutanoyl) 6 [3,7 dimethylocta 2,6 dienyl] 4 phenyl 2h chromen 2 one
5,7 dihydroxy 8 (3 methylbutanoyl) 6 [3,7 dimethylocta 2,6 dienyl] 4 phenyl 2h chromen 2 one
animal cell
animal experiment
apoptosis
article
bark
cell line
cell nucleus
cell viability
chromatin
chromatography
controlled study
drug isolation
drug structure
hydrogen peroxide
isomammeisin
mammea a/ba
Mesua kunstleri
mesuagenin c
mitochondrion
mouse
neuroprotection
neuroprotective agent
nonhuman
nuclear magnetic resonance spectroscopy
plant
plant extract
priority journal
staining
unclassified drug
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