5,7 dihydroxy 8 (2 methylbutanoyl) 6 [3,7 dimethylocta 2,6 dienyl] 4 phenyl 2h chromen 2 one 5,7 dihydroxy 8 (3 methylbutanoyl) 6 [3,7 dimethylocta 2,6 dienyl] 4 phenyl 2h chromen 2 one Mesua kunstleri animal cell animal experiment apoptosis article bark cell line cell nucleus cell viability chromatin chromatography controlled study drug isolation drug structure hydrogen peroxide isomammeisin mammea a/ba mesuagenin c mitochondrion mouse neuroprotection neuroprotective agent nonhuman nuclear magnetic resonance spectroscopy plant plant extract priority journal staining