Amikacin@SiO2 core@shell nanocarriers to treat pulmonal bacterial infections

Amikacin@SiO2 core@shell nanocarriers to treat pulmonal bacterial infections

AMC@SiO2 core@shell nanocarriers (AMC: amikacin) are realized and contain an exceptionally high drug load of 0.8 mg mg−1 (i.e. 80% AMC of total nanocarrier mass). They are prepared via a solvent-antisolvent approach with AMC nanoparticles formed in a first step, which are then covered and stabilised...

Full description

Bibliographic Details
Main Authors: Feldmann, C. (Author), Redinger, N. (Author), Rutschmann, M. (Author), Schaible, U.E (Author)
Format: Article
Language:English
Published: Royal Society of Chemistry 2023
Subjects:
Amikacin
Anti-solvents
Bacterial infections
Core shell
Dimethylsulphoxides
Drug delivery
Drug load
Mean diameter
Nanocarriers
One-pot synthesis
Particle size analysis
Shells (structures)
Silica
Silica shell
Silicon
Sols
Spectroscopic analysis
Synthesis (chemical)
X ray powder diffraction
Online Access:View Fulltext in Publisher

Internet

View Fulltext in Publisher

Similar Items