The synthesis of 2,2,3,3-tetrafluorinated galactose and glucose derivatives

The incorporation of polyfluorinated regions into carbohydrates has been proposed as a strategy to improve the typically low protein–carbohydrate affinity. The creation of a hydrophobic region, while maintaining a potential for attractive dipolar interactions (mediated by the polarised C–F bond) may...

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Bibliographic Details
Main Author: Golten, Samuel
Other Authors: Linclau, Bruno
Published: University of Southampton 2012
Subjects:
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.581472