SirT1 regulates bone mass in vivo through regulation of osteoblast and osteoclast differentiation
Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Biology, 2009. === Includes bibliographical references. === As mammals age, osteoblast numbers decrease while osteoclast numbers increase, resulting in age-related or post-menopausal osteoporosis. SirT1, the mammalian orthologue of yea...
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| Format: | Others |
| Language: | English |
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Massachusetts Institute of Technology
2009
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| Online Access: | http://hdl.handle.net/1721.1/47883 |