Evaluation of the Potential Impact of Ebola Virus Genomic Drift on the Efficacy of Sequence-Based Candidate Therapeutics

Until recently, Ebola virus (EBOV) was a rarely encountered human pathogen that caused disease among small populations with extraordinarily high lethality. At the end of 2013, EBOV initiated an unprecedented disease outbreak in West Africa that is still ongoing and has already caused thousands of de...

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Main Authors: Kugelman, Jeffrey R. (Author), Sanchez-Lockhart, Mariano (Author), Andersen, Kristian G. (Author), Gire, Stephen (Author), Park, Daniel J. (Author), Lin, Aaron E. (Author), Wohl, Shirlee (Author), Sabeti, Pardis C. (Author), Kuhn, Jens H. (Author), Palacios, Gustavo F. (Author), Sealfon, Rachel Sima (Contributor)
Other Authors: Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory (Contributor), Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science (Contributor)
Format: Article
Language:English
Published: American Society for Microbiology, 2015-02-11T16:09:18Z.
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