MICU2, a Paralog of MICU1, Resides within the Mitochondrial Uniporter Complex to Regulate Calcium Handling

MICU2, a Paralog of MICU1, Resides within the Mitochondrial Uniporter Complex to Regulate Calcium Handling

Mitochondrial calcium uptake is present in nearly all vertebrate tissues and is believed to be critical in shaping calcium signaling, regulating ATP synthesis and controlling cell death. Calcium uptake occurs through a channel called the uniporter that resides in the inner mitochondrial membrane. Re...

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Main Authors: Plovanich, Molly (Author), Bogorad, Roman (Contributor), Sancak, Yasemin (Author), Kamer, Kimberli J. (Author), Strittmatter, Laura (Author), Li, Andrew A. (Author), Girgis, Hany S. (Author), Kuchimanchi, Satya (Author), Groot, Jack De (Author), Speciner, Lauren (Author), Taneja, Nathan (Author), OShea, Jonathan (Author), Kotelianski, Victor E. (Contributor), Mootha, Vamsi K. (Author)
Other Authors: Koch Institute for Integrative Cancer Research at MIT (Contributor)
Format: Article
Language:English
Published: Public Library of Science, 2013-05-01T15:15:08Z.
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