Upstream open reading frames cause widespread reduction of protein expression and are polymorphic among humans

by Calvo, Sarah E., Pagliarini, David J., Mootha, Vamsi K.
Published 2009

Proteomic Mapping of Mitochondria in Living Cells via Spatially Restricted Enzymatic Tagging

by Martell, Jeffrey Daniel, Ting, Alice Y., Rhee, Hyun-Woo, Zou, Peng, Udeshi, Namrata D., Mootha, Vamsi K., Carr, Steven A.
Published 2015

A plasma signature of human mitochondrial disease revealed through metabolic profiling of spent media from cultured muscle cells

by Shaham, Oded, Slate, Nancy G., Goldberger, Olga A., Xu, Qiuwei, Ramanathan, Arvind, Souza, Amanda, Clish, Clary, Sims, Katherine, Mootha, Vamsi K.
Published 2011

Directed evolution of APEX2 for electron microscopy and proximity labeling

by Kamer, Kimberli J, Deerinck, Thomas J, Ellisman, Mark H, Mootha, Vamsi K, Lam, Stephanie Shih-Min, Martell, Jeffrey Daniel, Ting, Alice Y
Published 2017

Engineered ascorbate peroxidase as a genetically encoded reporter for electron microscopy

by Deerinck, Thomas J., Sancak, Yasemin, Poulos, Thomas L., Mootha, Vamsi K., Sosinsky, Gina E., Ellisman, Mark H., Martell, Jeffrey Daniel, Ting, Alice Y.
Published 2015

MICU2, a Paralog of MICU1, Resides within the Mitochondrial Uniporter Complex to Regulate Calcium Handling

by Plovanich, Molly, Bogorad, Roman, Sancak, Yasemin, Kamer, Kimberli J., Strittmatter, Laura, Li, Andrew A., Girgis, Hany S., Kuchimanchi, Satya, Groot, Jack De, Speciner, Lauren, Taneja, Nathan, OShea, Jonathan, Kotelianski, Victor E., Mootha, Vamsi K.
Published 2013

Mitochondrial dysfunction remodels one-carbon metabolism in human cells

by Bao, Xiaoyan Robert, Ong, Shao-En, Goldberger, Olga, Peng, Jun, Sharma, Rohit, Thompson, Dawn A, Vafai, Scott B, Cox, Andrew G, Marutani, Eizo, Ichinose, Fumito, Goessling, Wolfram, Carr, Steven A, Clish, Clary B, Mootha, Vamsi K, Regev, Aviv
Published 2016

Mutations in MTFMT Underlie a Human Disorder of Formylation Causing Impaired Mitochondrial Translation

by Tucker, Elena J, Hershman, Steven G, Belcher-Timme, Casey A, Patel, Jinal, Goldberger, Olga A., Christodoulou, John, Silberstein, Jonathon M, McKenzie, Matthew, Ryan, Michael T, Compton, Alison G, Jaffe, Jacob D., Carr, Steven A., Calvo, Sarah E., RajBhandary, Uttam L, Thorburn, David R, Mootha, Vamsi K., Koehrer, Caroline
Published 2014

How many human proteoforms are there?

by Aebersold, Ruedi, Agar, Jeffrey N, Amster, I Jonathan, Baker, Mark S, Bertozzi, Carolyn R, Boja, Emily S, Costello, Catherine E, Cravatt, Benjamin F, Fenselau, Catherine, Garcia, Benjamin A, Ge, Ying, Gunawardena, Jeremy, Hendrickson, Ronald C, Hergenrother, Paul J, Huber, Christian G, Ivanov, Alexander R, Jensen, Ole N, Jewett, Michael C, Kelleher, Neil L, Krogan, Nevan J, Larsen, Martin R, Loo, Joseph A, Ogorzalek Loo, Rachel R, Lundberg, Emma, MacCoss, Michael J, Mallick, Parag, Mootha, Vamsi K, Mrksich, Milan, Muir, Tom W, Patrie, Steven M, Pesavento, James J, Pitteri, Sharon J, Rodriguez, Henry, Saghatelian, Alan, Sandoval, Wendy, Schlüter, Hartmut, Sechi, Salvatore, Slavoff, Sarah A, Smith, Lloyd M, Snyder, Michael P, Thomas, Paul M, Uhlén, Mathias, Van Eyk, Jennifer E, Vidal, Marc, Walt, David R, White, Forest M, Williams, Evan R, Wohlschlager, Therese, Wysocki, Vicki H, Yates, Nathan A, Young, Nicolas L, Zhang, Bing, Kiessling, Laura L
Published 2019