Deletion of DXZ4 on the human inactive X chromosome alters higher-order genome architecture
During interphase, the inactive X chromosome (Xi) is largely transcriptionally silent and adopts an unusual 3D configuration known as the "Barr body." Despite the importance of X chromosome inactivation, little is known about this 3D conformation. We recently showed that in humans the Xi c...
Main Authors: | , , , , , , , , , , , , , |
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Other Authors: | |
Format: | Article |
Language: | English |
Published: |
Proceedings of the National Academy of Sciences,
2018-04-17T17:51:38Z.
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Subjects: | |
Online Access: | Get fulltext |