Characterizing the Altered Cellular Proteome Induced by the Stress-Independent Activation of Heat Shock Factor 1

The heat shock response is an evolutionarily conserved, stress-responsive signaling pathway that adapts cellular proteostasis in response to pathologic insult. In metazoans, the heat shock response primarily functions through the posttranslational activation of heat shock factor 1 (HSF1), a stress-r...

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Bibliographic Details
Main Authors: Ryno, Lisa M. (Author), Genereux, Joseph C. (Author), Naito, Tadasuke (Author), Morimoto, Richard I. (Author), Powers, Evan T. (Author), Shoulders, Matthew D. (Contributor), Wiseman, R. Luke (Author)
Other Authors: Massachusetts Institute of Technology. Department of Chemistry (Contributor)
Format: Article
Language:English
Published: American Chemical Society (ACS), 2018-02-12T16:06:56Z.
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