Characterization of an A-Site Selective Protein Disulfide Isomerase A1 Inhibitor

by Chen, Kenny, Shoulders, Matthew D.
Published 2020

Directed evolution in mammalian cells

by Hendel, Samuel J, Shoulders, Matthew D.
Published 2022

Genetic Engineering by DNA Recombineering

by Papa, Louis John, Shoulders, Matthew D.
Published 2021

A Processive Protein Chimera Introduces Mutations across Defined DNA Regions In Vivo

by Moore, Christopher Lawrence, Papa, Louis John, Shoulders, Matthew D.
Published 2020

A Sensitive, Nonradioactive Assay for Zn(II) Uptake into Metazoan Cells

by Richardson, Christopher E. R., Nolan, Elizabeth Marie, Shoulders, Matthew D., Lippard, Stephen J.
Published 2020

Enhanced ER proteostasis and temperature differentially impact the mutational tolerance of influenza hemagglutinin

by Phillips, Angela Marie, Gonzalez, Luna O., Butty, Vincent L G, Shoulders, Matthew D.
Published 2020

Collagen's enigmatic, highly conserved N -glycan has an essential proteostatic function

by Li, Rasia C, Wong, Madeline Y, DiChiara, Andrew S, Hosseini, Azade S, Shoulders, Matthew D
Published 2022

Multidimensional chemical control of CRISPR-Cas9

by Maji, Basudeb, Shoulders, Matthew D, Choudhary, Amit, Moore, Christopher, Zetsche, Bernd, Volz, Sara E., Zhang, Feng
Published 2017

Transportable, Chemical Genetic Methodology for the Small Molecule-Mediated Inhibition of Heat Shock Factor 1

by Moore, Christopher Lawrence, Dewal, Mahender, Nekongo, Emmanuel E, Santiago, Sebasthian, Lu, Nancy B., Levine, Stuart S., Shoulders, Matthew D.
Published 2017

Characterizing the Altered Cellular Proteome Induced by the Stress-Independent Activation of Heat Shock Factor 1

by Ryno, Lisa M., Genereux, Joseph C., Naito, Tadasuke, Morimoto, Richard I., Powers, Evan T., Shoulders, Matthew D., Wiseman, R. Luke
Published 2018

A Method for Selective Depletion of Zn(II) Ions from Complex Biological Media and Evaluation of Cellular Consequences of Zn(II) Deficiency

by Richardson, Christopher E. R., Cunden, Lisa Stephanie, Butty, Vincent L G, Nolan, Elizabeth Marie, Lippard, Stephen J., Shoulders, Matthew D.
Published 2020

Mapping and Exploring the Collagen-I Proteostasis Network

by DiChiara, Andrew Stephen, Taylor, Rebecca J., Wong, Madeline Y., Doan, Ngoc Duc, Del Rosario, Amanda M, Shoulders, Matthew D.
Published 2018

XBP1s Links the Unfolded Protein Response to the Molecular Architecture of Mature N-Glycans

by Antonopoulos, Aristotelis, Haslam, Stuart M, Dell, Anne, Dewal, Mahender, DiChiara, Andrew Stephen, Taylor, Rebecca J., Harmon, Chyleigh J., Shoulders, Matthew D.
Published 2017

CRISPR/Cas9 editing to generate a heterozygous COL2A1 p.G1170S human chondrodysplasia iPSC line, MCRIi019-A-2, in a control iPSC line, MCRIi019-A

by Kung, Louise HW, Sampurno, Lisa, Yammine, Kathryn M, Graham, Alison, McDonald, Penny, Bateman, John F, Shoulders, Matthew D, Lamandé, Shireen R
Published 2022

CRISPR/Cas9 editing to generate a heterozygous COL2A1 p.G1170S human chondrodysplasia iPSC line, MCRIi019-A-2, in a control iPSC line, MCRIi019-A

by Kung, Louise H.W, Sampurno, Lisa, Yammine, Kathryn M., Graham, Alison, McDonald, Penny, Bateman, John F., Shoulders, Matthew D., Lamandé, Shireen R.
Published 2022

XBP1s activation can globally remodel N-glycan structure distribution patterns

by Wong, Madeline Y., Dewal, Mahender, Taylor, Rebecca J., Whittaker, Charles A., Phyo, Pyae, Shoulders, Matthew D., Chen, Kenny,Ph. D.Massachusetts Institute of Technology
Published 2020

A cysteine-based molecular code informs collagen C-propeptide assembly

by DiChiara, Andrew Stephen, Li, Rasia C., Suen, Patreece H., Hosseini, Azade S., Taylor, Rebecca J., Weickhardt, Alexander F., Malhotra, Diya, Shoulders, Matthew D.
Published 2020

Destabilized adaptive influenza variants critical for innate immune system escape are potentiated by host chaperones

by Phillips, Angela Marie, Ponomarenko, Anna, Butty, Vincent L G, Whittaker, Charles A., Moore, Christopher Lawrence, Shoulders, Matthew D., Chen, Kenny,Ph. D.Massachusetts Institute of Technology
Published 2020

A High-Throughput Assay for Collagen Secretion Suggests an Unanticipated Role for Hsp90 in Collagen Production

by Wong, Madeline Y., Doan, Ngoc Duc, DiChiara, Andrew Stephen, Papa, Louis John, Cheah, Jaime H, Soule, Christian K., Watson, Nicki E., Shoulders, Matthew D.
Published 2020

Host proteostasis modulates influenza evolution

by McHugh, Sean M, Lin, Yu-Shan, Phillips, Angela Marie, Gonzalez, Luna O., Nekongo, Emmanuel E, Ponomarenko, Anna, Butty, Vincent L G, Levine, Stuart S., Mirny, Leonid A, Shoulders, Matthew D.
Published 2017