Visualization of Chromatin Decompaction and Break Site Extrusion as Predicted by Statistical Polymer Modeling of Single-Locus Trajectories

Chromatin moves with subdiffusive and spatially constrained dynamics within the cell nucleus. Here, we use single-locus tracking by time-lapse fluorescence microscopy to uncover information regarding the forces that influence chromatin movement following the induction of a persistent DNA double-stra...

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Bibliographic Details
Main Authors: Amitai, Assaf (Contributor), Seeber, Andrew (Author), Gasser, Susan M. (Author), Holcman, David (Author)
Other Authors: Massachusetts Institute of Technology. Institute for Medical Engineering & Science (Contributor)
Format: Article
Language:English
Published: 2211-1247, 2017-06-13T18:18:01Z.
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