Direct Lineage Conversion of Adult Mouse Liver Cells and B Lymphocytes to Neural Stem Cells

Overexpression of transcription factors has been used to directly reprogram somatic cells into a range of other differentiated cell types, including multipotent neural stem cells (NSCs), that can be used to generate neurons and glia. However, the ability to maintain the NSC state independent of the...

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Bibliographic Details
Main Authors: John P. Cassady, Ana C. D’Alessio, Sovan Sarkar, Vardhan S. Dani, Zi Peng Fan, Kibibi Ganz, Reinhard Roessler, Mriganka Sur, Richard A. Young, Rudolf Jaenisch
Format: Article
Language:English
Published: Elsevier 2014-12-01
Series:Stem Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2213671114003075