SLCO3A1, A novel crohn's disease-associated gene, regulates nf-κB activity and associates with intestinal perforation.

<h4>Background & aims</h4>To date, only one gene (TNFSF15) has been identified and validated as a Crohn's disease (CD)-associated gene in non-Caucasian populations. This study was designed to identify novel CD-associated single nucleotide polymorphisms (SNPs)/genes and to valida...

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Main Authors: Shu-Chen Wei, Yan-Yin Tan, Meng-Tzu Weng, Liang-Chuan Lai, Jen-Hao Hsiao, Eric Y Chuang, Chia-Tung Shun, Deng-Cheng Wu, Ai-Wen Kao, Chiao-Shung Chuang, Yen-Hsuan Ni, Ming-Jium Shieh, Chien-Chih Tung, Yun Chen, Cheng-Yi Wang, Ramnik J Xavier, Daniel K Podolsky, Jau-Min Wong
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24945726/?tool=EBI