Establishment and Characterization of a Sclerosing Spindle Cell Rhabdomyosarcoma Cell Line with a Complex Genomic Profile

Establishment and Characterization of a Sclerosing Spindle Cell Rhabdomyosarcoma Cell Line with a Complex Genomic Profile

Sclerosing spindle cell rhabdomyosarcoma (SSRMS) is a rare rhabdomyosarcomas (RMS) subtype. Especially cases bearing a myogenic differentiation 1 (<i>MYOD1</i>) mutation are characterized by a high recurrence and metastasis rate, often leading to a fatal outcome. SSRMS cell lines are val...

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Bibliographic Details
Main Authors: Sabine Schleicher, Stefan Grote, Elke Malenke, Kenneth Chun-Ho Chan, Martin Schaller, Birgit Fehrenbacher, Rosa Riester, Torsten Kluba, Leonie Frauenfeld, Hans Boesmueller, Gudrun Göhring, Brigitte Schlegelberger, Rupert Handgretinger, Hans-Georg Kopp, Frank Traub, Karen A. Boehme
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Cells
Subjects:
rhabdomyosarcoma
sclerosing
spindle cell
cell line establishment
stem cell
genetics
Online Access:https://www.mdpi.com/2073-4409/9/12/2668

Internet

https://www.mdpi.com/2073-4409/9/12/2668

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