High-Throughput Gene and Protein Analysis Revealed the Response of Disc Cells to Vitamin D, Depending on the VDR FokI Variants

High-Throughput Gene and Protein Analysis Revealed the Response of Disc Cells to Vitamin D, Depending on the VDR FokI Variants

Vitamin D showed a protective effect on intervertebral disc degeneration (IDD) although conflicting evidence is reported. An explanation could be due to the presence of the FokI functional variant in the vitamin D receptor (<i>VDR</i>), observed as associated with spine pathologies. The...

Full description

Bibliographic Details
Main Authors: Alessandra Colombini, Paola De Luca, Davide Cangelosi, Carlotta Perucca Orfei, Enrico Ragni, Marco Viganò, Michela Malacarne, Mauro Castagnetta, Marco Brayda-Bruno, Domenico Coviello, Laura de Girolamo
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:International Journal of Molecular Sciences
Subjects:
intervertebral disc
vitamin D receptor gene polymorphism
vitamin D
inflammation
gene profile
protein profile
Online Access:https://www.mdpi.com/1422-0067/22/17/9603

Internet

https://www.mdpi.com/1422-0067/22/17/9603

Similar Items