IL-6-mediated activation of Stat3α prevents trauma/hemorrhagic shock-induced liver inflammation.

Trauma complicated by hemorrhagic shock (T/HS) is the leading cause of morbidity and mortality in the United States for individuals under the age of 44 years. Initial survivors are susceptible to developing multiple organ failure (MOF), which is thought to be caused, at least in part, by excessive o...

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Bibliographic Details
Main Authors: Ana Moran, Stephen A Thacker, Ayse Akcan Arikan, Mary-Ann A Mastrangelo, Yong Wu, Bi Yu, David J Tweardy
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3127578?pdf=render