Contribution of STAT3 to Inflammatory and Fibrotic Diseases and Prospects for its Targeting for Treatment

by Moses M. Kasembeli, Uddalak Bharadwaj, Prema Robinson, David J. Tweardy
Published 2018-08-01

Substance P Signaling Contributes to Granuloma Formation in Taenia crassiceps Infection, a Murine Model of Cysticercosis

by Armandina Garza, David J. Tweardy, Joel Weinstock, Balaji Viswanathan, Prema Robinson
Published 2010-01-01

Contribution of the Type II Chaperonin, TRiC/CCT, to Oncogenesis

by Soung-Hun Roh, Moses Kasembeli, Deenadayalan Bakthavatsalam, Wah Chiu, David J. Tweardy
Published 2015-11-01

Chemical probes that competitively and selectively inhibit Stat3 activation.

by Xuejun Xu, Moses M Kasembeli, Xueqing Jiang, Benjamin J Tweardy, David J Tweardy
Published 2009-01-01

Substance P Receptor Signaling Mediates Doxorubicin-Induced Cardiomyocyte Apoptosis and Triple-Negative Breast Cancer Chemoresistance

by Prema Robinson, Moses Kasembeli, Uddalak Bharadwaj, Nikita Engineer, Kris T. Eckols, David J. Tweardy
Published 2016-01-01

Modulation of STAT3 folding and function by TRiC/CCT chaperonin.

by Moses Kasembeli, Wilson Chun Yu Lau, Soung-Hun Roh, T Kris Eckols, Judith Frydman, Wah Chiu, David J Tweardy
Published 2014-04-01

Substance P causes seizures in neurocysticercosis.

by Prema Robinson, Armandina Garza, Joel Weinstock, Jose A Serpa, Jerry Clay Goodman, Kristian T Eckols, Bahrom Firozgary, David J Tweardy
Published 2012-02-01

Monoclonal Antibodies Specific for STAT3β Reveal Its Contribution to Constitutive STAT3 Phosphorylation in Breast Cancer

by Uddalak Bharadwaj, Moses M. Kasembeli, T. Kris Eckols, Mikhail Kolosov, Paul Lang, Kurt Christensen, Dean P. Edwards, David J. Tweardy
Published 2014-09-01

IL-6-mediated activation of Stat3α prevents trauma/hemorrhagic shock-induced liver inflammation.

by Ana Moran, Stephen A Thacker, Ayse Akcan Arikan, Mary-Ann A Mastrangelo, Yong Wu, Bi Yu, David J Tweardy
Published 2011-01-01

Correction: Prevention of Hypovolemic Circulatory Collapse by IL-6 Activated Stat3

by Jeffrey A. Alten, Ana Moran, Anna I. Tsimelzon, Mary-Ann A. Mastrangelo, Susan G. Hilsenbeck, Valeria Poli, David J. Tweardy
Published 2008-01-01

Prevention of hypovolemic circulatory collapse by IL-6 activated Stat3.

by Jeffrey A Alten, Ana Moran, Anna I Tsimelzon, Mary-Ann A Mastrangelo, Susan G Hilsenbeck, Valeria Poli, David J Tweardy
Published 2008-02-01

Correction: Prevention of Hypovolemic Circulatory Collapse by IL-6 Activated Stat3.

by Jeffrey A. Alten, Ana Moran, Anna I. Tsimelzon, Mary-Ann A. Mastrangelo, Susan G. Hilsenbeck, Valeria Poli, David J. Tweardy
Published 2008-01-01

PARP Inhibition Suppresses Growth of EGFR-Mutant Cancers by Targeting Nuclear PKM2

by Nan Li, Lin Feng, Hui Liu, Jiadong Wang, Moses Kasembeli, My Kim Tran, David J. Tweardy, Steven Hsesheng Lin, Junjie Chen
Published 2016-04-01

Correction: Selective Small Molecule Stat3 Inhibitor Reduces Breast Cancer Tumor-Initiating Cells and Improves Recurrence Free Survival in a Human-Xenograft Model

by Bhuvanesh Dave, Melissa D. Landis, Lacey E. Dobrolecki, Meng-Fen Wu, Xiaomei Zhang, Thomas F. Westbrook, Susan G. Hilsenbeck, Dan Liu, Michael T. Lewis, David J. Tweardy, Jenny C. Chang
Published 2012-01-01

Selective small molecule Stat3 inhibitor reduces breast cancer tumor-initiating cells and improves recurrence free survival in a human-xenograft model.

by Bhuvanesh Dave, Melissa D Landis, David J Tweardy, Jenny C Chang, Lacey E Dobrolecki, Meng-Fen Wu, Xiaomei Zhang, Thomas F Westbrook, Susan G Hilsenbeck, Dan Liu, Michael T Lewis
Published 2012-01-01

Correction: Selective Small Molecule Stat3 Inhibitor Reduces Breast Cancer Tumor-Initiating Cells and Improves Recurrence Free Survival in a Human-Xenograft Model.

by Bhuvanesh Dave, Melissa D. Landis, Lacey E. Dobrolecki, Meng-Fen Wu, Xiaomei Zhang, Thomas F. Westbrook, Susan G. Hilsenbeck, Dan Liu, Michael T. Lewis, David J. Tweardy, Jenny C. Chang
Published 2012-01-01

Correction: Piperlongumine Blocks JAK2-STAT3 to Inhibit Collagen-Induced Platelet Reactivity Independent of Reactive Oxygen Species†.

by Hengjie Yuan, Katie L Houck, Ye Tian, Uddalak Bharadwaj, Ken Hull, Zhou Zhou, Mingzhao Zhu, Xiaoping Wu, David J Tweardy, Daniel Romo, Xiaoyun Fu, Yanjun Zhang, Jianning Zhang, Jing-fei Dong
Published 2016-01-01

Piperlongumine Blocks JAK2-STAT3 to Inhibit Collagen-Induced Platelet Reactivity Independent of Reactive Oxygen Species.

by Hengjie Yuan, Katie L Houck, Ye Tian, Uddalak Bharadwaj, Ken Hull, Zhou Zhou, Mingzhao Zhu, Xiaoping Wu, David J Tweardy, Daniel Romo, Xiaoyun Fu, Yanjun Zhang, Jianning Zhang, Jing-fei Dong
Published 2015-01-01

Intratumoral CD40 activation and checkpoint blockade induces T cell-mediated eradication of melanoma in the brain

by Manisha Singh, Christina Vianden, Mark J. Cantwell, Zhimin Dai, Zhilan Xiao, Meenu Sharma, Hiep Khong, Ashvin R. Jaiswal, Faisal Faak, Yared Hailemichael, L. M. E. Janssen, Uddalak Bharadwaj, Michael A. Curran, Adi Diab, Roland L. Bassett, David J. Tweardy, Patrick Hwu, Willem W. Overwijk
Published 2017-11-01

Mechanism and preclinical prevention of increased breast cancer risk caused by pregnancy

by Svasti Haricharan, Jie Dong, Sarah Hein, Jay P Reddy, Zhijun Du, Michael Toneff, Kimberly Holloway, Susan G Hilsenbeck, Shixia Huang, Rachel Atkinson, Wendy Woodward, Sonali Jindal, Virginia F Borges, Carolina Gutierrez, Hong Zhang, Pepper J Schedin, C Kent Osborne, David J Tweardy, Yi Li
Published 2013-12-01