Understanding T cell phenotype for the design of effective chimeric antigen receptor T cell therapies

Understanding T cell phenotype for the design of effective chimeric antigen receptor T cell therapies

Rapid advances in immunotherapy have identified adoptive cell transfer as one of the most promising approaches for the treatment of cancers. Large numbers of cancer reactive T lymphocytes can be generated ex vivo from patient blood by genetic modification to express chimeric antigen receptors (CAR)...

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Bibliographic Details
Main Authors: Michael H Kershaw, Daniela GM Tantalo, Amanda J Oliver, Bianca von Scheidt, Aaron J Harrison, Scott N Mueller, Clare Y Slaney
Format: Article
Language:English
Published: BMJ Publishing Group 2021-05-01
Series:Journal for ImmunoTherapy of Cancer
Online Access:https://jitc.bmj.com/content/9/5/e002555.full

Internet

https://jitc.bmj.com/content/9/5/e002555.full

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