Challenges and Opportunities for Effective Cancer Immunotherapies

by Clare Y. Slaney, Michael H. Kershaw
Published 2020-10-01

Environmental enrichment does not impact on tumor growth in mice [v1; ref status: indexed, http://f1000r.es/18c]

by Jennifer A Westwood, Phillip K Darcy, Michael H Kershaw
Published 2013-06-01

Genetic Redirection of T Cells for the Treatment of Pancreatic Cancer

by Aesha I. Ali, Aesha I. Ali, Amanda J. Oliver, Amanda J. Oliver, Tinaz Samiei, Tinaz Samiei, Jack D. Chan, Jack D. Chan, Michael H. Kershaw, Michael H. Kershaw, Clare Y. Slaney, Clare Y. Slaney
Published 2019-02-01

Tissue-Dependent Tumor Microenvironments and Their Impact on Immunotherapy Responses

by Amanda J. Oliver, Amanda J. Oliver, Peter K. H. Lau, Peter K. H. Lau, Ashleigh S. Unsworth, Ashleigh S. Unsworth, Sherene Loi, Sherene Loi, Phillip K. Darcy, Phillip K. Darcy, Michael H. Kershaw, Michael H. Kershaw, Clare Y. Slaney, Clare Y. Slaney
Published 2018-01-01

Routes of delivery for CpG and anti-CD137 for the treatment of orthotopic kidney tumors in mice.

by Jennifer A Westwood, Titaina C U Potdevin Hunnam, Hollie J Pegram, Rodney J Hicks, Phillip K Darcy, Michael H Kershaw
Published 2014-01-01

Understanding T cell phenotype for the design of effective chimeric antigen receptor T cell therapies

by Michael H Kershaw, Daniela GM Tantalo, Amanda J Oliver, Bianca von Scheidt, Aaron J Harrison, Scott N Mueller, Clare Y Slaney
Published 2021-05-01

Bi-Allelic Mutations in STXBP2 Reveal a Complementary Role for STXBP1 in Cytotoxic Lymphocyte Killing

by Jamie A. Lopez, Jamie A. Lopez, Tahereh Noori, Adrian Minson, Lu Li Jovanoska, Kevin Thia, Michael S. Hildebrand, Hedieh Akhlaghi, Phillip K. Darcy, Phillip K. Darcy, Michael H. Kershaw, Michael H. Kershaw, Natasha J. Brown, Andrew Grigg, Joseph A. Trapani, Joseph A. Trapani, Ilia Voskoboinik, Ilia Voskoboinik
Published 2018-03-01

Expression of a Chimeric Antigen Receptor in Multiple Leukocyte Lineages in Transgenic Mice.

by Carmen S M Yong, Jennifer A Westwood, Jan Schröder, Anthony T Papenfuss, Bianca von Scheidt, Maria Moeller, Christel Devaud, Phillip K Darcy, Michael H Kershaw
Published 2015-01-01

Engineering T cell function using chimeric antigen receptors identified using a DNA library approach.

by Connie P M Duong, Jennifer A Westwood, Carmen S M Yong, Amanda Murphy, Christel Devaud, Liza B John, Phillip K Darcy, Michael H Kershaw
Published 2013-01-01

Generating CAR T cells from tumor-infiltrating lymphocytes

by Jane K. Mills, Melissa A. Henderson, Lauren Giuffrida, Pasquale Petrone, Jennifer A. Westwood, Phillip K. Darcy, Paul J. Neeson, Michael H. Kershaw, David E. Gyorki
Published 2021-05-01

Primary and metastatic breast tumors cross-talk to influence immunotherapy responses

by Amanda J Oliver, Simon P Keam, Bianca von Scheidt, Damien J Zanker, Aaron J Harrison, Daniela GM Tantalo, Phillip K Darcy, Michael H Kershaw, Clare Y Slaney
Published 2020-01-01

Foxp3 expression in macrophages associated with RENCA tumors in mice.

by Christel Devaud, Carmen S M Yong, Liza B John, Jennifer A Westwood, Connie P M Duong, Colin M House, Delphine Denoyer, Jason Li, Phillip K Darcy, Michael H Kershaw
Published 2014-01-01

Embryonic Lethality in Homozygous Human Her-2 Transgenic Mice Due to Disruption of the Pds5b Gene.

by Carmen S M Yong, Janelle Sharkey, Belinda Duscio, Ben Venville, Wei-Zen Wei, Richard F Jones, Clare Y Slaney, Gisela Mir Arnau, Anthony T Papenfuss, Jan Schröder, Phillip K Darcy, Michael H Kershaw
Published 2015-01-01

Enhancing chimeric antigen receptor T‐cell immunotherapy against cancer using a nanoemulsion‐based vaccine targeting cross‐presenting dendritic cells

by Jack D Chan, Bianca vonScheidt, Bijun Zeng, Amanda J Oliver, Ashleigh S Davey, Aesha I Ali, Ranjeny Thomas, Joseph A Trapani, Phillip K Darcy, Michael H Kershaw, Riccardo Dolcetti, Clare Y Slaney
Published 2020-01-01

Tissue‐specific tumor microenvironments influence responses to immunotherapies

by Amanda J Oliver, Ashleigh S Davey, Simon P Keam, Sherly Mardiana, Jack D Chan, Bianca vonScheidt, Paul A Beavis, Imran G House, Jonas RM Van Audernaerde, Phillip K Darcy, Michael H Kershaw, Clare Y Slaney
Published 2019-01-01

Novel combination immunotherapy for pancreatic cancer: potent anti‐tumor effects with CD40 agonist and interleukin‐15 treatment

by Jonas RM Van Audenaerde, Elly Marcq, Bianca vonScheidt, Ashleigh S Davey, Amanda J Oliver, Jorrit De Waele, Delphine Quatannens, Jinthe Van Loenhout, Patrick Pauwels, Geert Roeyen, Filip Lardon, Clare Y Slaney, Marc Peeters, Michael H Kershaw, Phillip K Darcy, Evelien LJM Smits
Published 2020-01-01

Agonist immunotherapy restores T cell function following MEK inhibition improving efficacy in breast cancer

by Sathana Dushyanthen, Zhi Ling Teo, Franco Caramia, Peter Savas, Christopher P. Mintoff, Balaji Virassamy, Melissa A. Henderson, Stephen J. Luen, Mariam Mansour, Michael H. Kershaw, Joseph A. Trapani, Paul J. Neeson, Roberto Salgado, Grant A. McArthur, Justin M. Balko, Paul A. Beavis, Phillip K. Darcy, Sherene Loi
Published 2017-09-01