Effect of tranexamic acid on coagulation and fibrinolysis in women with postpartum haemorrhage (WOMAN-ETAC): a single-centre, randomised, double-blind, placebo-controlled trial [version 1; referees: 2 approved]

Background: Postpartum haemorrhage (PPH) is a leading cause of maternal death. The WOMAN trial showed that tranexamic acid (TXA) reduces death due to bleeding in women with PPH. We evaluated the effect of TXA on fibrinolysis and coagulation in a sample of WOMAN trial participants. Methods: Adult wom...

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Main Authors: Haleema Shakur-Still, Ian Roberts, Bukola Fawole, Modupe Kuti, Oladapo O. Olayemi, Adenike Bello, Sumaya Huque, Olayinka Ogunbode, Taiwo Kotila, Chris Aimakhu, Olujide A. Okunade, Tolulase Olutogun, Cecilia O. Adetayo, Kastriot Dallaku, Ulrich Mansmann, Beverley J. Hunt, Tracey Pepple, Eni Balogun
Format: Article
Language:English
Published: Wellcome 2018-08-01
Series:Wellcome Open Research
Online Access:https://wellcomeopenresearch.org/articles/3-100/v1