A nested randomised trial of the effect of tranexamic acid on intracranial haemorrhage and infarction in traumatic brain injury (CRASH-3 trial intracranial bleeding mechanistic stu...

by Abda Mahmood, Ian Roberts, Haleema Shakur-Still
Published 2019-11-01

A nested randomised trial of the effect of tranexamic acid on intracranial haemorrhage and infarction in traumatic brain injury (CRASH-3 trial intracranial bleeding mechanistic stu...

by Abda Mahmood, Ian Roberts, Haleema Shakur-Still
Published 2019-01-01

Accuracy of time to treatment estimates in the CRASH-3 clinical trial: impact on the trial results

by Raoul Mansukhani, Lauren Frimley, Haleema Shakur-Still, Linda Sharples, Ian Roberts
Published 2020-07-01

Cost-effectiveness analysis of tranexamic acid for the treatment of traumatic brain injury, based on the results of the CRASH-3 randomised trial: a decision modelling approach

by Ian Roberts, Fiona E Lecky, Jack Williams, Rizwana Chaudhri, Haleema Shakur-Still
Published 2020-09-01

Trial management: we need a cadre of high-class triallists to deliver the answers that patients need

by Danielle Beaumont, Monica Arribas, Lauren Frimley, Eni Balogun, Ian Roberts, Haleema Shakur-Still
Published 2019-06-01

Risk factors for peripartum hysterectomy among women with postpartum haemorrhage: analysis of data from the WOMAN trial

by Sumaya Huque, Ian Roberts, Bukola Fawole, Rizwana Chaudhri, Sabaratnam Arulkumaran, Haleema Shakur-Still
Published 2018-05-01

Risk factors for blood transfusion in traumatic and postpartum hemorrhage patients: Analysis of the CRASH-2 and WOMAN trials.

by David A Kolin, Haleema Shakur-Still, Adenike Bello, Rizwana Chaudhri, Imelda Bates, Ian Roberts
Published 2020-01-01

Outcome measures in clinical trials of treatments for acute severe haemorrhage

by Amy Brenner, Monica Arribas, Jack Cuzick, Vipul Jairath, Simon Stanworth, Katharine Ker, Haleema Shakur-Still, Ian Roberts
Published 2018-10-01

The impact of early outcome events on the effect of tranexamic acid in post-partum haemorrhage: an exploratory subgroup analysis of the WOMAN trial

by Amy Brenner, Haleema Shakur-Still, Rizwana Chaudhri, Bukola Fawole, Sabaratnam Arulkumaran, Ian Roberts, on behalf of the WOMAN Trial Collaborators
Published 2018-06-01

No effect of tranexamic acid on platelet function and thrombin generation (ETAPlaT) in postpartum haemorrhage: a randomised placebo-controlled trial [version 1; peer review: 2 appr...

by Kastriot Dallaku, Haleema Shakur-Still, Danielle Beaumont, Ian Roberts, Sumaya Huque, Maria Delius, Stefan Holdenrieder, Orion Gliozheni, Ulrich Mansmann
Published 2019-02-01

WOMAN-PharmacoTXA trial: Study protocol for a randomised controlled trial to assess the pharmacokinetics and pharmacodynamics of intramuscular, intravenous and oral administration...

by Monica Arribas, Ian Roberts, Rizwana Chaudhri, Amber Geer, Danielle Prowse, Mwansa Ketty Lubeya, Aasia Kayani, Kiran Javaid, Stanislas Grassin-Delyle, Haleema Shakur-Still
Published 2021-06-01

The WOMAN trial: clinical and contextual factors surrounding the deaths of 483 women following post-partum haemorrhage in developing countries

by Roberto Picetti, Lori Miller, Haleema Shakur-Still, Tracey Pepple, Danielle Beaumont, Eni Balogun, Etienne Asonganyi, Rizwana Chaudhri, Mohamed El-Sheikh, Bellington Vwalika, Sabaratnam Arulkumaran, Ian Roberts, on behalf of the WOMAN trial collaborators
Published 2020-07-01

Understanding the neuroprotective effect of tranexamic acid: an exploratory analysis of the CRASH-3 randomised trial

by Amy Brenner, Antonio Belli, Rizwana Chaudhri, Timothy Coats, Lauren Frimley, Sabariah Faizah Jamaluddin, Rashid Jooma, Raoul Mansukhani, Peter Sandercock, Haleema Shakur-Still, Temitayo Shokunbi, Ian Roberts, On behalf of the CRASH-3 trial collaborators
Published 2020-11-01

Tranexamic acid for the prevention of postpartum bleeding in women with anaemia: study protocol for an international, randomised, double-blind, placebo-controlled trial

by Katharine Ker, Ian Roberts, Rizwana Chaudhri, Bukola Fawole, Danielle Beaumont, Eni Balogun, Danielle Prowse, Tracey Pepple, Kiran Javaid, Aasia Kayani, Sabaratnam Arulkumaran, Imelda Bates, Haleema Shakur-Still, on behalf of the WOMAN-2 trial collaborators
Published 2018-12-01

The effect of statins on muscle symptoms in primary care: the StatinWISE series of 200 N-of-1 RCTs

by Emily Herrett, Elizabeth Williamson, Kieran Brack, Alexander Perkins, Andrew Thayne, Haleema Shakur-Still, Ian Roberts, Danielle Prowse, Danielle Beaumont, Zahra Jamal, Ben Goldacre, Tjeerd van Staa, Thomas M MacDonald, Jane Armitage, Michael Moore, Maurice Hoffman, Liam Smeeth
Published 2021-03-01

Effect of tranexamic acid on coagulation and fibrinolysis in women with postpartum haemorrhage (WOMAN-ETAC): a single-centre, randomised, double-blind, placebo-controlled trial [ve...

by Haleema Shakur-Still, Ian Roberts, Bukola Fawole, Modupe Kuti, Oladapo O. Olayemi, Adenike Bello, Sumaya Huque, Olayinka Ogunbode, Taiwo Kotila, Chris Aimakhu, Olujide A. Okunade, Tolulase Olutogun, Cecilia O. Adetayo, Kastriot Dallaku, Ulrich Mansmann, Beverley J. Hunt, Tracey Pepple, Eni Balogun
Published 2018-08-01

Tranexamic acid for acute gastrointestinal bleeding (the HALT-IT trial): statistical analysis plan for an international, randomised, double-blind, placebo-controlled trial

by Amy Brenner, Adefemi Afolabi, Syed Masroor Ahmad, Monica Arribas, Rizwana Chaudhri, Timothy Coats, Jack Cuzick, Ian Gilmore, Christopher Hawkey, Vipul Jairath, Kiran Javaid, Aasia Kayani, Muttiullah Mutti, Muhammad Arif Nadeem, Haleema Shakur-Still, Simon Stanworth, Andrew Veitch, Ian Roberts, HALT-IT Trial Collaborators
Published 2019-07-01

Tranexamic acid to reduce head injury death in people with traumatic brain injury: the CRASH-3 international RCT

by Ian Roberts, Haleema Shakur-Still, Amy Aeron-Thomas, Danielle Beaumont, Antonio Belli, Amy Brenner, Madeleine Cargill, Rizwana Chaudhri, Nicolas Douglas, Lauren Frimley, Catherine Gilliam, Amber Geer, Zahra Jamal, Rashid Jooma, Raoul Mansukhani, Alec Miners, Jason Pott, Danielle Prowse, Temitayo Shokunbi, Jack Williams
Published 2021-04-01