Temporal dynamics of SARS-CoV-2 mutation accumulation within and across infected hosts.

Analysis of SARS-CoV-2 genetic diversity within infected hosts can provide insight into the generation and spread of new viral variants and may enable high resolution inference of transmission chains. However, little is known about temporal aspects of SARS-CoV-2 intrahost diversity and the extent to...

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Bibliographic Details
Main Authors: Andrew L Valesano, Kalee E Rumfelt, Derek E Dimcheff, Christopher N Blair, William J Fitzsimmons, Joshua G Petrie, Emily T Martin, Adam S Lauring
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-04-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1009499