A mathematical-biological joint effort to investigate the tumor-initiating ability of Cancer Stem Cells.

The involvement of Cancer Stem Cells (CSCs) in tumor progression and tumor recurrence is one of the most studied subjects in current cancer research. The CSC hypothesis states that cancer cell populations are characterized by a hierarchical structure that affects cancer progression. Due to the compl...

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Bibliographic Details
Main Authors: Chiara Fornari, Marco Beccuti, Stefania Lanzardo, Laura Conti, Gianfranco Balbo, Federica Cavallo, Raffaele A Calogero, Francesca Cordero
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4153566?pdf=render