Junín virus infection activates the type I interferon pathway in a RIG-I-dependent manner.

Junín virus infection activates the type I interferon pathway in a RIG-I-dependent manner.

Junín virus (JUNV), an arenavirus, is the causative agent of Argentine hemorrhagic fever, an infectious human disease with 15-30% case fatality. The pathogenesis of AHF is still not well understood. Elevated levels of interferon and cytokines are reported in AHF patients, which might be correlated t...

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Bibliographic Details
Main Authors: Cheng Huang, Olga A Kolokoltsova, Nadezdha E Yun, Alexey V Seregin, Allison L Poussard, Aida G Walker, Allan R Brasier, Yingxin Zhao, Bing Tian, Juan Carlos de la Torre, Slobodan Paessler
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC3358329?pdf=render

Internet

http://europepmc.org/articles/PMC3358329?pdf=render

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