RSV Reprograms the CDK9•BRD4 Chromatin Remodeling Complex to Couple Innate Inflammation to Airway Remodeling

by Allan R. Brasier
Published 2020-04-01

Targeting inducible epigenetic reprogramming pathways in chronic airway remodeling

by Allan R Brasier, Istvan Boldogh
Published 2019-10-01

Nanoapproaches to Modifying Epigenetics of Epithelial Mesenchymal Transition for Treatment of Pulmonary Fibrosis

by Melissa Skibba, Adam Drelich, Michael Poellmann, Seungpyo Hong, Seungpyo Hong, Seungpyo Hong, Allan R. Brasier, Allan R. Brasier
Published 2020-12-01

Alternative mRNA Processing of Innate Response Pathways in Respiratory Syncytial Virus (RSV) Infection

by Xiaofang Xu, Morgan Mann, Dianhua Qiao, Allan R. Brasier
Published 2021-01-01

The SWI/SNF-Related, Matrix Associated, Actin-Dependent Regulator of Chromatin A4 Core Complex Represses Respiratory Syncytial Virus-Induced Syncytia Formation and Subepithelial My...

by Xiaofang Xu, Dianhua Qiao, Chenyang Dong, Morgan Mann, Roberto P. Garofalo, Sunduz Keles, Sunduz Keles, Allan R. Brasier, Allan R. Brasier
Published 2021-03-01

Respiratory Syncytial Virus Infection Induces Chromatin Remodeling to Activate Growth Factor and Extracellular Matrix Secretion Pathways

by Xiaofang Xu, Dianhua Qiao, Morgan Mann, Roberto P. Garofalo, Allan R. Brasier
Published 2020-07-01

Discovery of RSV-Induced BRD4 Protein Interactions Using Native Immunoprecipitation and Parallel Accumulation—Serial Fragmentation (PASEF) Mass Spectrometry

by Morgan Mann, David S. Roberts, Yanlong Zhu, Yi Li, Jia Zhou, Ying Ge, Allan R. Brasier
Published 2021-03-01

Systems biology approaches to understanding Epithelial Mesenchymal Transition (EMT) in mucosal remodeling and signaling in asthma

by Talha Ijaz, Konrad Pazdrak, Mridul Kalita, Rolf Konig, Sanjeev Choudhary, Bing Tian, Istvan Boldogh, Allan R. Brasier
Published 2014-01-01

Dynamic cross talk model of the epithelial innate immune response to double-stranded RNA stimulation: coordinated dynamics emerging from cell-level noise.

by Roberto Bertolusso, Bing Tian, Yingxin Zhao, Leoncio Vergara, Aqeeb Sabree, Marta Iwanaszko, Tomasz Lipniacki, Allan R Brasier, Marek Kimmel
Published 2014-01-01

Expression of an IKKgamma splice variant determines IRF3 and canonical NF-kappaB pathway utilization in ssRNA virus infection.

by Ping Liu, Muping Lu, Bing Tian, Kui Li, Roberto P Garofalo, Deborah Prusak, Thomas G Wood, Allan R Brasier
Published 2009-11-01

Selective Antagonists of the Bronchiolar Epithelial NF-κB-Bromodomain-Containing Protein 4 Pathway in Viral-Induced Airway Inflammation

by Bing Tian, Zhiqing Liu, Jun Yang, Hong Sun, Yingxin Zhao, Maki Wakamiya, Haiying Chen, Erik Rytting, Jia Zhou, Allan R. Brasier
Published 2018-04-01

Cell fate in antiviral response arises in the crosstalk of IRF, NF-κB and JAK/STAT pathways

by Maciej Czerkies, Zbigniew Korwek, Wiktor Prus, Marek Kochańczyk, Joanna Jaruszewicz-Błońska, Karolina Tudelska, Sławomir Błoński, Marek Kimmel, Allan R. Brasier, Tomasz Lipniacki
Published 2018-02-01

Systems Approaches to Modeling Chronic Mucosal Inflammation

by Mridul Kalita, Bing Tian, Boning Gao, Sanjeev Choudhary, Thomas G. Wood, Joseph R. Carmical, Istvan Boldogh, Sankar Mitra, John D. Minna, Allan R. Brasier
Published 2013-01-01

Effects of storage temperature on airway exosome integrity for diagnostic and functional analyses

by Rosario Maroto, Yingxin Zhao, Mohammad Jamaluddin, Vsevolod L. Popov, Hongwang Wang, Madumali Kalubowilage, Yueqing Zhang, Jonathan Luisi, Hong Sun, Christopher T. Culbertson, Stefan H. Bossmann, Massoud Motamedi, Allan R. Brasier
Published 2017-12-01

Effects of the stimuli-dependent enrichment of 8-oxoguanine DNA glycosylase1 on chromatinized DNA

by Wenjing Hao, Tianyang Qi, Lang Pan, Ruoxi Wang, Bing Zhu, Leopoldo Aguilera-Aguirre, Zsolt Radak, Tapas K. Hazra, Spiros A. Vlahopoulos, Attila Bacsi, Allan R. Brasier, Xueqing Ba, Istvan Boldogh
Published 2018-09-01

Junín virus infection activates the type I interferon pathway in a RIG-I-dependent manner.

by Cheng Huang, Olga A Kolokoltsova, Nadezdha E Yun, Alexey V Seregin, Allison L Poussard, Aida G Walker, Allan R Brasier, Yingxin Zhao, Bing Tian, Juan Carlos de la Torre, Slobodan Paessler
Published 2012-01-01

Changes in Proteome Profile of Peripheral Blood Mononuclear Cells in Chronic Chagas Disease.

by Nisha Jain Garg, Kizhake V Soman, Maria P Zago, Sue-Jie Koo, Heidi Spratt, Susan Stafford, Zinzi N Blell, Shivali Gupta, Julio Nuñez Burgos, Natalia Barrientos, Allan R Brasier, John E Wiktorowicz
Published 2016-02-01

RIG-I enhanced interferon independent apoptosis upon Junin virus infection.

by Olga A Kolokoltsova, Ashley M Grant, Cheng Huang, Jennifer K Smith, Allison L Poussard, Bing Tian, Allan R Brasier, Clarence J Peters, Chien-Te Kent Tseng, Juan C de la Torre, Slobodan Paessler
Published 2014-01-01

Dysregulation of RBFOX2 Is an Early Event in Cardiac Pathogenesis of Diabetes

by Curtis A. Nutter, Elizabeth A. Jaworski, Sunil K. Verma, Vaibhav Deshmukh, Qiongling Wang, Olga B. Botvinnik, Mario J. Lozano, Ismail J. Abass, Talha Ijaz, Allan R. Brasier, Nisha J. Garg, Xander H.T. Wehrens, Gene W. Yeo, Muge N. Kuyumcu-Martinez
Published 2016-06-01

PEGylated Domain I of Beta-2-Glycoprotein I Inhibits the Binding, Coagulopathic, and Thrombogenic Properties of IgG From Patients With the Antiphospholipid Syndrome

by Thomas C. R. McDonnell, Rohan Willis, Charis Pericleous, Vera M. Ripoll, Ian P. Giles, David. A. Isenberg, David. A. Isenberg, Allan R. Brasier, Emilio B. Gonzalez, Elizabeth Papalardo, Zurina Romay-Penabad, Mohammad Jamaluddin, Yiannis Ioannou, Yiannis Ioannou, Anisur Rahman
Published 2018-10-01