Immunological correlates of mycobacterial growth inhibition describe a spectrum of tuberculosis infection

Abstract A major contribution to the burden of Tuberculosis (TB) comes from latent Mycobacterium tuberculosis infections (LTBI) becoming clinically active. TB and LTBI probably exist as a spectrum and currently there are no correlates available to identify individuals with LTBI most at risk of devel...

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Bibliographic Details
Main Authors: Matthew K. O’Shea, Rachel Tanner, Julius Müller, Stephanie A. Harris, Danny Wright, Lisa Stockdale, Elena Stylianou, Iman Satti, Steven G. Smith, James Dunbar, Thomas E. Fletcher, Martin Dedicoat, Adam F. Cunningham, Helen McShane
Format: Article
Language:English
Published: Nature Publishing Group 2018-09-01
Series:Scientific Reports
Subjects:
Online Access:https://doi.org/10.1038/s41598-018-32755-x