Integration of transcriptomics, proteomics, and microRNA analyses reveals novel microRNA regulation of targets in the mammalian inner ear.

Integration of transcriptomics, proteomics, and microRNA analyses reveals novel microRNA regulation of targets in the mammalian inner ear.

We have employed a novel approach for the identification of functionally important microRNA (miRNA)-target interactions, integrating miRNA, transcriptome and proteome profiles and advanced in silico analysis using the FAME algorithm. Since miRNAs play a crucial role in the inner ear, demonstrated by...

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Bibliographic Details
Main Authors: Tal Elkan-Miller, Igor Ulitsky, Ronna Hertzano, Anya Rudnicki, Amiel A Dror, Danielle R Lenz, Ran Elkon, Martin Irmler, Johannes Beckers, Ron Shamir, Karen B Avraham
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3071727?pdf=render

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http://europepmc.org/articles/PMC3071727?pdf=render

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