Identification of C/EBPβ target genes in ALK+ anaplastic large cell lymphoma (ALCL) by gene expression profiling and chromatin immunoprecipitation.

by Irina Bonzheim, Martin Irmler, Margit Klier-Richter, Julia Steinhilber, Nataša Anastasov, Sabine Schäfer, Patrick Adam, Johannes Beckers, Mark Raffeld, Falko Fend, Leticia Quintanilla-Martinez
Published 2013-01-01

Integration of transcriptomics, proteomics, and microRNA analyses reveals novel microRNA regulation of targets in the mammalian inner ear.

by Tal Elkan-Miller, Igor Ulitsky, Ronna Hertzano, Anya Rudnicki, Amiel A Dror, Danielle R Lenz, Ran Elkon, Martin Irmler, Johannes Beckers, Ron Shamir, Karen B Avraham
Published 2011-01-01

The Notch ligand DNER regulates macrophage IFNγ release in chronic obstructive pulmonary diseaseResearch in context

by Carolina Ballester-López, Thomas M. Conlon, Zeynep Ertüz, Flavia R. Greiffo, Martin Irmler, Stijn E. Verleden, Johannes Beckers, Isis E. Fernandez, Oliver Eickelberg, Ali Önder Yildirim
Published 2019-05-01

Dynamic adoption of anergy by antigen-exhausted CD4+ T cells

by Anne Trefzer, Pallavi Kadam, Shu-Hung Wang, Stefanie Pennavaria, Benedikt Lober, Batuhan Akçabozan, Jan Kranich, Thomas Brocker, Naoko Nakano, Martin Irmler, Johannes Beckers, Tobias Straub, Reinhard Obst
Published 2021-02-01

Fibroblast growth factor 21 is elevated in metabolically unhealthy obesity and affects lipid deposition, adipogenesis, and adipokine secretion of human abdominal subcutaneous adipo...

by Lucia Berti, Martin Irmler, Marty Zdichavsky, Tobias Meile, Anja Böhm, Norbert Stefan, Andreas Fritsche, Johannes Beckers, Alfred Königsrainer, Hans-Ulrich Häring, Martin Hrabě de Angelis, Harald Staiger
Published 2015-07-01

Maternal Pre-Pregnancy Obesity Is Associated with Altered Placental Transcriptome.

by Signe Altmäe, Maria Teresa Segura, Francisco J Esteban, Sabine Bartel, Pilar Brandi, Martin Irmler, Johannes Beckers, Hans Demmelmair, Carmen López-Sabater, Berthold Koletzko, Susanne Krauss-Etschmann, Cristina Campoy
Published 2017-01-01

Transcriptomic analysis comparing mouse strains with extreme total lung capacities identifies novel candidate genes for pulmonary function

by Leema George, Ankita Mitra, Tania A. Thimraj, Martin Irmler, Sangeetha Vishweswaraiah, Lars Lunding, Dorothea Hühn, Alicia Madurga, Johannes Beckers, Heinz Fehrenbach, Swapna Upadhyay, Holger Schulz, George D. Leikauf, Koustav Ganguly
Published 2017-08-01

Correction: In Vivo Functional Requirement of the Mouse Ifitm1 Gene for Germ Cell Development, Interferon Mediated Immune Response and Somitogenesis

by Ingeborg Klymiuk, Lukas Kenner, Thure Adler, Dirk H. Busch, Auke Boersma, Martin Irmler, Barbara Fridrich, Valérie Gailus-Durner, Helmut Fuchs, Nicole Leitner, Mathias Müller, Ralf Kühn, Michaela Schlederer, Irina Treise, Martin Hrabě de Angelis, Johannes Beckers
Published 2012-01-01

In vivo functional requirement of the mouse Ifitm1 gene for germ cell development, interferon mediated immune response and somitogenesis.

by Ingeborg Klymiuk, Lukas Kenner, Thure Adler, Dirk H Busch, Auke Boersma, Martin Irmler, Barbara Fridrich, Valérie Gailus-Durner, Helmut Fuchs, Nicole Leitner, Mathias Müller, Ralf Kühn, Michaela Schlederer, Irina Treise, Martin Hrabě de Angelis, Johannes Beckers
Published 2012-01-01

Correction: Functional Requirement of the Mouse Gene for Germ Cell Development, Interferon Mediated Immune Response and Somitogenesis.

by Ingeborg Klymiuk, Lukas Kenner, Thure Adler, Dirk H. Busch, Auke Boersma, Martin Irmler, Barbara Fridrich, Valérie Gailus-Durner, Helmut Fuchs, Nicole Leitner, Mathias Müller, Ralf Kühn, Michaela Schlederer, Irina Treise, Martin Hrabě de Angelis, Johannes Beckers
Published 2012-01-01

Correlation guided Network Integration (CoNI) reveals novel genes affecting hepatic metabolism

by Valentina S. Klaus, Sonja C. Schriever, José Manuel Monroy Kuhn, Andreas Peter, Martin Irmler, Janina Tokarz, Cornelia Prehn, Gabi Kastenmüller, Johannes Beckers, Jerzy Adamski, Alfred Königsrainer, Timo D. Müller, Martin Heni, Matthias H. Tschöp, Paul T. Pfluger, Dominik Lutter
Published 2021-11-01

Point mutations in the PDX1 transactivation domain impair human β-cell development and function

by Xianming Wang, Michael Sterr, Ansarullah, Ingo Burtscher, Anika Böttcher, Julia Beckenbauer, Johanna Siehler, Thomas Meitinger, Hans-Ulrich Häring, Harald Staiger, Filippo M. Cernilogar, Gunnar Schotta, Martin Irmler, Johannes Beckers, Christopher V.E. Wright, Mostafa Bakhti, Heiko Lickert
Published 2019-06-01

Stem-Cell-like Properties and Epithelial Plasticity Arise as Stable Traits after Transient Twist1 Activation

by Johanna M. Schmidt, Elena Panzilius, Harald S. Bartsch, Martin Irmler, Johannes Beckers, Vijayalakshmi Kari, Jelena R. Linnemann, Diana Dragoi, Benjamin Hirschi, Uwe J. Kloos, Steffen Sass, Fabian Theis, Steffen Kahlert, Steven A. Johnsen, Karl Sotlar, Christina H. Scheel
Published 2015-01-01

The Aryl Hydrocarbon Receptor Pathway Defines the Time Frame for Restorative Neurogenesis

by Rossella Di Giaimo, Tamara Durovic, Pablo Barquin, Anita Kociaj, Tjasa Lepko, Sven Aschenbroich, Christopher T. Breunig, Martin Irmler, Filippo M. Cernilogar, Gunnar Schotta, Joana S. Barbosa, Dietrich Trümbach, Emily Violette Baumgart, Andrea M. Neuner, Johannes Beckers, Wolfgang Wurst, Stefan H. Stricker, Jovica Ninkovic
Published 2018-12-01

Dose-Dependent and Subset-Specific Regulation of Midbrain Dopaminergic Neuron Differentiation by LEF1-Mediated WNT1/b-Catenin Signaling

by Parivash Nouri, Sebastian Götz, Benedict Rauser, Martin Irmler, Changgeng Peng, Changgeng Peng, Dietrich Trümbach, Christian Kempny, Carina G. Lechermeier, Agnes Bryniok, Andrea Dlugos, Ellen Euchner, Johannes Beckers, Johannes Beckers, Johannes Beckers, Claude Brodski, Claudia Klümper, Wolfgang Wurst, Wolfgang Wurst, Wolfgang Wurst, Wolfgang Wurst, Nilima Prakash
Published 2020-10-01

Genome-wide analysis of PDX1 target genes in human pancreatic progenitors

by Xianming Wang, Michael Sterr, Ingo Burtscher, Shen Chen, Anja Hieronimus, Fausto Machicao, Harald Staiger, Hans-Ulrich Häring, Gabriele Lederer, Thomas Meitinger, Filippo M. Cernilogar, Gunnar Schotta, Martin Irmler, Johannes Beckers, Martin Hrabě de Angelis, Michael Ray, Christopher V.E. Wright, Mostafa Bakhti, Heiko Lickert
Published 2018-03-01

Specific Induction of Double Negative B Cells During Protective and Pathogenic Immune Responses

by Christoph Ruschil, Christoph Ruschil, Gisela Gabernet, Gildas Lepennetier, Simon Heumos, Miriam Kaminski, Zsuzsanna Hracsko, Martin Irmler, Johannes Beckers, Johannes Beckers, Johannes Beckers, Ulf Ziemann, Ulf Ziemann, Sven Nahnsen, Gregory P. Owens, Jeffrey L. Bennett, Jeffrey L. Bennett, Bernhard Hemmer, Bernhard Hemmer, Markus C. Kowarik, Markus C. Kowarik, Markus C. Kowarik
Published 2020-12-01

Cholesterol metabolism promotes B‐cell positioning during immune pathogenesis of chronic obstructive pulmonary disease

by Jie Jia, Thomas M Conlon, Rim SJ Sarker, Demet Taşdemir, Natalia F Smirnova, Barkha Srivastava, Stijn E Verleden, Gizem Güneş, Xiao Wu, Cornelia Prehn, Jiaqi Gao, Katharina Heinzelmann, Jutta Lintelmann, Martin Irmler, Stefan Pfeiffer, Michael Schloter, Ralf Zimmermann, Martin Hrabé de Angelis, Johannes Beckers, Jerzy Adamski, Hasan Bayram, Oliver Eickelberg, Ali Önder Yildirim
Published 2018-05-01

Combination therapies induce cancer cell death through the integrated stress response and disturbed pyrimidine metabolism

by Goetz Hartleben, Kenji Schorpp, Yun Kwon, Barbara Betz, Foivos‐Filippos Tsokanos, Zahra Dantes, Arlett Schäfer, Ina Rothenaigner, José Manuel Monroy Kuhn, Pauline Morigny, Lisa Mehr, Sean Lin, Susanne Seitz, Janina Tokarz, Anna Artati, Jerzy Adamsky, Oliver Plettenburg, Dominik Lutter, Martin Irmler, Johannes Beckers, Maximilian Reichert, Kamyar Hadian, Anja Zeigerer, Stephan Herzig, Mauricio Berriel Diaz
Published 2021-04-01

Influence of wood species on toxicity of log-wood stove combustion aerosols: a parallel animal and air-liquid interface cell exposure study on spruce and pine smoke

by Tuukka Ihantola, Sebastiano Di Bucchianico, Mikko Happo, Mika Ihalainen, Oskari Uski, Stefanie Bauer, Kari Kuuspalo, Olli Sippula, Jarkko Tissari, Sebastian Oeder, Anni Hartikainen, Teemu J. Rönkkö, Maria-Viola Martikainen, Kati Huttunen, Petra Vartiainen, Heikki Suhonen, Miika Kortelainen, Heikki Lamberg, Ari Leskinen, Martin Sklorz, Bernhard Michalke, Marco Dilger, Carsten Weiss, Gunnar Dittmar, Johannes Beckers, Martin Irmler, Jeroen Buters, Joana Candeias, Hendryk Czech, Pasi Yli-Pirilä, Gülcin Abbaszade, Gert Jakobi, Jürgen Orasche, Jürgen Schnelle-Kreis, Tamara Kanashova, Erwin Karg, Thorsten Streibel, Johannes Passig, Henri Hakkarainen, Jorma Jokiniemi, Ralf Zimmermann, Maija-Riitta Hirvonen, Pasi I. Jalava
Published 2020-06-01