Lack of a skeletal muscle phenotype in adult human bone marrow stromal cells following xenogeneic-free expansion

Lack of a skeletal muscle phenotype in adult human bone marrow stromal cells following xenogeneic-free expansion

Abstract Background Many studies have elegantly shown that murine and rat bone marrow-derived mesenchymal stromal cells (bmMSCs) contribute to muscle regeneration and improve muscle function. Yet, the ability of transplanted human bmMSCs to manifest myogenic potential shows conflicting results. Whil...

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Bibliographic Details
Main Authors: Dominik Barisic, Marita Erb, Marie Follo, Dahlia Al-Mudaris, Bernd Rolauffs, Melanie L. Hart
Format: Article
Language:English
Published: BMC 2020-02-01
Series:Stem Cell Research & Therapy
Subjects:
Mesenchymal stromal cells
MSCs
Myogenesis
Neurogenesis
Coronin 1b
GAP-43
Online Access:http://link.springer.com/article/10.1186/s13287-020-1587-0

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http://link.springer.com/article/10.1186/s13287-020-1587-0

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