Mechanotransduction and Stiffness-Sensing: Mechanisms and Opportunities to Control Multiple Molecular Aspects of Cell Phenotype as a Design Cornerstone of Cell-Instructive Biomater...

by Mischa Selig, Jasmin C. Lauer, Melanie L. Hart, Bernd Rolauffs
Published 2020-07-01

Articular Chondrocyte Phenotype Regulation through the Cytoskeleton and the Signaling Processes That Originate from or Converge on the Cytoskeleton: Towards a Novel Understanding o...

by Jasmin C. Lauer, Mischa Selig, Melanie L. Hart, Bodo Kurz, Bernd Rolauffs
Published 2021-03-01

Anti-Inflammatory Therapeutic Approaches to Prevent or Delay Post-Traumatic Osteoarthritis (PTOA) of the Knee Joint with a Focus on Sustained Delivery Approaches

by Christine M. Khella, Judith M. Horvath, Rojiar Asgarian, Bernd Rolauffs, Melanie L. Hart
Published 2021-07-01

An Evidence-Based Systematic Review of Human Knee Post-Traumatic Osteoarthritis (PTOA): Timeline of Clinical Presentation and Disease Markers, Comparison of Knee Joint PTOA Models...

by Christine M. Khella, Rojiar Asgarian, Judith M. Horvath, Bernd Rolauffs, Melanie L. Hart
Published 2021-02-01

Shaping the Cell and the Future: Recent Advancements in Biophysical Aspects Relevant to Regenerative Medicine

by Melanie L. Hart, Jasmin C. Lauer, Mischa Selig, Martha Hanak, Brandan Walters, Bernd Rolauffs
Published 2017-12-01

Lack of a skeletal muscle phenotype in adult human bone marrow stromal cells following xenogeneic-free expansion

by Dominik Barisic, Marita Erb, Marie Follo, Dahlia Al-Mudaris, Bernd Rolauffs, Melanie L. Hart
Published 2020-02-01

Engineering the geometrical shape of mesenchymal stromal cells through defined cyclic stretch regimens

by Brandan Walters, Tatiana Uynuk-Ool, Miriam Rothdiener, Julian Palm, Melanie L. Hart, Jan P. Stegemann, Bernd Rolauffs
Published 2017-07-01

Towards a Treatment of Stress Urinary Incontinence: Application of Mesenchymal Stromal Cells for Regeneration of the Sphincter Muscle

by Wilhelm K. Aicher, Melanie L. Hart, Jan Stallkamp, Mario Klünder, Michael Ederer, Oliver Sawodny, Martin Vaegler, Bastian Amend, Karl D. Sievert, Arnulf Stenzl
Published 2014-02-01

Regeneration of Degenerated Urinary Sphincter Muscles: Improved Stem Cell-Based Therapies and Novel Imaging Technologies

by Bastian Amend, Martin Vaegler, Kerstin Fuchs, Julia G. Mannheim, Susanne Will, Ulrich Kramer, Melanie L. Hart, Wouter Feitz, Christopher Chapple, Arnulf Stenzl, Wilhelm K. Aicher
Published 2015-11-01

Smooth Muscle-Like Cells Generated from Human Mesenchymal Stromal Cells Display Marker Gene Expression and Electrophysiological Competence Comparable to Bladder Smooth Muscle Cells...

by Juliane Brun, Katrin A Lutz, Katharina M H Neumayer, Gerd Klein, Tanja Seeger, Tatiana Uynuk-Ool, Katharina Wörgötter, Sandra Schmid, Udo Kraushaar, Elke Guenther, Bernd Rolauffs, Wilhelm K Aicher, Melanie L Hart
Published 2015-01-01